Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.34 |
| ▸ | TAS1R3 | Q7RTX0 | 3/20 | 0.34 |
| ▸ | TAS1R1 | Q7RTX1 | 3/20 | 0.34 |
| ▸ | MGLL | Q99685 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | PIM1 | P11309 | 1/20 | 0.33 |
| ▸ | SNCA | P37840 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL300884 | 0.86 | CA12 (0.42) | ALDH1A1HPGDCA12CA1CA9 | |
| SCHEMBL43877 | 0.85 | ALDH1A1 (0.51) | ALDH1A1HPGDCA12CA1CA9 | |
| SCHEMBL18530063 | 0.84 | ALDH1A1 (0.50) | ALDH1A1HPGDCA12CA1CA9 | |
| SCHEMBL9554693 | 0.83 | PTPN1 (0.35) | ALDH1A1HPGDCA12CA1CA9 | |
| SCHEMBL21160109 | 0.82 | MAPK1 (0.40) | ALDH1A1KMT2AMGLLTDP1MAPK1 | |
| SCHEMBL16005095 | 0.81 | ALDH1A1 (0.37) | ALDH1A1HPGDCA12CA1CA9 | |
| SCHEMBL22046417 | 0.81 | F3 (0.44) | ALDH1A1HPGDCA12CA1CA9 | |
| SCHEMBL13455758 | 0.81 | SMN1; SMN2 (0.44) | ALDH1A1HPGDCA12CA1CA9 | |
| SCHEMBL14156433 | 0.80 | L3MBTL1 (0.40) | ALDH1A1HPGDKMT2ATDP1SNCA | |
| SCHEMBL9626036 | 0.80 | GRIN2D (0.38) | ALDH1A1CA1KMT2AKDM4EMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112812228-B | UCST enhanced acrylamide copolymer and preparation method thereof | 中国医学科学院生物医学工程研究所 | 2024-06-25 | — | — | CN | disclosed |
| WO-2016183359-A1 | SILICON BASED DRUG CONJUGATES AND METHODS OF USING SAME | BLINKBIO, INC. (US) | 2016-11-17 | — | — | WO | disclosed |
| US-9206271-B2 | Fully backbone degradable and functionalizable polymers derived from the ring-opening metathesis polymerization (ROMP) | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2015-12-08 | — | — | US | disclosed |
| US-9206271-B2 | Fully backbone degradable and functionalizable polymers derived from the ring-opening metathesis polymerization (ROMP) | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2015-12-08 | — | — | US | disclosed |
| US-20130281644-A1 | Fully Backbone Degradable and Functionalizable Polymers Derived from the Ring-Opening Metathesis Polymerization (ROMP) | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2013-10-24 | — | — | US | disclosed |
| US-8426649-B2 | Cyclopropenones and the photochemical generation of cyclic alkynes therefrom | UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) | 2013-04-23 | — | — | US | disclosed |
| US-20120053299-A1 | Cyclopropenones and the Photochemical Generation of Cyclic Alkynes Therefrom | UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) | 2012-03-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120053299-A1 | Cyclopropenones and the Photochemical Generation of Cyclic Alkynes Therefrom | WEE1, WEE2, MPI | ALDH1A1 205/4885HPGD 508/4885CA12 151/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.