Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 7/20 | 0.50 |
| ▸ | TSPO | P30536 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | EGFR | P00533 | 2/20 | 0.42 |
| ▸ | SRC | P12931 | 1/20 | 0.42 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.42 |
| ▸ | TUBB | P07437 | 2/20 | 0.42 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.42 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.42 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.42 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.42 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7236310 | 0.94 | TACR1 (0.49) | TACR1TSPOKDM4EALDH1A1CYP1A2 | |
| SCHEMBL7798973 | 0.94 | TACR1 (0.48) | TACR1TSPOKDM4EALDH1A1CYP1A2 | |
| SCHEMBL7242930 | 0.87 | PPARG (0.50) | TACR1TSPOKDM4EALDH1A1CYP1A2 | |
| SCHEMBL22160195 | 0.86 | TACR1 (0.51) | TACR1CYP2C9EGFRSRC | |
| SCHEMBL7238513 | 0.84 | TSPO (0.56) | TACR1TSPOKDM4EALDH1A1CYP1A2 | |
| SCHEMBL7233540 | 0.83 | TSPO (0.47) | TACR1TSPOKDM4EALDH1A1CYP1A2 | |
| SCHEMBL7241810 | 0.82 | CXCR2 (0.56) | TACR1TSPOCYP2C9 | |
| SCHEMBL7790369 | 0.82 | CXCR2 (0.52) | TACR1TSPOKDM4EALDH1A1CYP1A2 | |
| SCHEMBL7232797 | 0.81 | TACR1 (0.43) | TACR1TSPOKDM4EALDH1A1CYP1A2 | |
| SCHEMBL7238595 | 0.80 | CXCR2 (0.53) | TACR1TSPOKDM4EALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6605633-B1 | Such as 5-Bromo-2-phenyl-1H-indole-3-butanoic acid | FOURNIER INDUSTRIE ET SANTE (FR) | 2003-08-12 | — | — | US | disclosed |