Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSPO | P30536 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | TACR1 | P25103 | 5/20 | 0.54 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.47 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7241810 | 0.93 | CXCR2 (0.56) | TSPOTACR1CXCR2 | |
| SCHEMBL7238595 | 0.93 | CXCR2 (0.53) | TSPOKDM4EALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL6805872 | 0.92 | TSPO (0.47) | TSPOKDM4EALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL7241409 | 0.91 | TSPO (0.47) | TSPOKDM4EALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL7232861 | 0.91 | TSPO (0.47) | TSPOKDM4EALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL7236310 | 0.91 | TACR1 (0.49) | TSPOKDM4EALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL7232319 | 0.91 | CXCR2 (0.55) | TSPOTACR1CXCR2 | |
| SCHEMBL7242413 | 0.90 | TSPO (0.46) | TSPOKDM4EALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL7232831 | 0.89 | TACR1 (0.45) | TSPOKDM4EALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL7232669 | 0.89 | TACR1 (0.45) | TSPOKDM4EALDH1A1CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6605633-B1 | Such as 5-Bromo-2-phenyl-1H-indole-3-butanoic acid | FOURNIER INDUSTRIE ET SANTE (FR) | 2003-08-12 | — | — | US | disclosed |