Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.39 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.37 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.37 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.35 |
| ▸ | HTR3B | O95264 | 1/20 | 0.35 |
| ▸ | HTR3A | P46098 | 1/20 | 0.35 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.35 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.34 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.34 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7234311 | 0.89 | USP30 (0.39) | USP30MAPK11MAPK14HTR3EHTR3B | |
| SCHEMBL7075331 | 0.89 | USP30 (0.39) | USP30MAPK11MAPK14HTR3EHTR3B | |
| SCHEMBL7230337 | 0.88 | MAPK11 (0.49) | USP30MAPK11MAPK14HTR3EHTR3B | |
| SCHEMBL7226023 | 0.88 | USP30 (0.41) | USP30MAPK11MAPK14HTR3EHTR3B | |
| Hydrochloric Acid SCHEMBL7077995 | 0.88 | USP30 (0.39) | USP30MAPK11MAPK14HTR3EHTR3B | |
| SCHEMBL7225952 | 0.88 | MAPK14 (0.45) | USP30MAPK11MAPK14HTR3EHTR3B | |
| SCHEMBL7225473 | 0.86 | MAPK11 (0.42) | USP30MAPK11MAPK14HTR3EHTR3B | |
| SCHEMBL7231086 | 0.85 | USP30 (0.43) | USP30MAPK11MAPK14HTR3EHTR3B | |
| SCHEMBL7233270 | 0.85 | HDAC3 (0.48) | USP30MAPK11MAPK14HTR3EHTR3B | |
| SCHEMBL7071274 | 0.85 | USP30 (0.53) | USP30HTR3EHTR3BHTR3AHTR3D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6562816-B2 | Alpha 7 nicotine acetylcholine receptor agonist anti-psychotic agent, with reduced side effects | PHARMACIA & UPJOHN COMPANY | 2003-05-13 | — | — | US | claimed |
| US-6562816-B2 | Alpha 7 nicotine acetylcholine receptor agonist anti-psychotic agent, with reduced side effects | PHARMACIA & UPJOHN COMPANY | 2003-05-13 | — | — | US | disclosed |