Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP17A1 | P05093 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8160351 | 0.83 | CYP17A1 (0.57) | CYP17A1ALDH1A1MAPTHPGDSMN1; SMN2 | |
| SCHEMBL724475 | 0.77 | TSHR (0.45) | CYP17A1ALDH1A1MAPTHPGDSMN1; SMN2 | |
| SCHEMBL19383233 | 0.76 | CYP17A1 (0.57) | CYP17A1ALDH1A1MAPTHPGDSMN1; SMN2 | |
| SCHEMBL8161302 | 0.76 | CYP17A1 (0.50) | CYP17A1ALDH1A1MAPTHPGDSMN1; SMN2 | |
| SCHEMBL6675359 | 0.76 | TSHR (0.44) | CYP17A1ALDH1A1MAPTHPGDSMN1; SMN2 | |
| SCHEMBL6673857 | 0.75 | PNMT (0.40) | ALDH1A1NPC1RAB9ACYP1A2CYP3A4 | |
| SCHEMBL7166658 | 0.73 | CYP17A1 (0.55) | CYP17A1ALDH1A1MAPTHPGDSMN1; SMN2 | |
| SCHEMBL7642376 | 0.73 | CYP17A1 (0.55) | CYP17A1ALDH1A1MAPTHPGDSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL9068742 | 0.73 | PNMT (0.38) | CYP17A1NPC1RAB9AHTR2BDRD2 | |
| Hydrochloric Acid SCHEMBL9165902 | 0.73 | PNMT (0.38) | NPC1RAB9AHTR2BDRD2HTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2226326-B1 | METHOD FOR PRODUCING ORGANIC ALKALI METAL COMPOUND AND METHOD FOR PRODUCING ORGANIC TRANSITION METAL COMPOUND | MITSUI CHEMICALS INC (JP) | 2016-02-17 | — | — | EP | disclosed |
| US-8409480-B2 | Process for preparing organic alkali metal compound and organic transition metal compound | MITSUI CHEMICALS, INC. (JP) | 2013-04-02 | — | — | US | disclosed |
| US-20120049391-A1 | PROCESS FOR PREPARING ORGANIC ALKALI METAL COMPOUND AND ORGANIC TRANSITION METAL COMPOUND | MITSUI CHEMICALS, INC. | 2012-03-01 | — | — | US | disclosed |
| EP-2226326-A1 | METHOD FOR PRODUCING ORGANIC ALKALI METAL COMPOUND AND METHOD FOR PRODUCING ORGANIC TRANSITION METAL COMPOUND | Mitsui Chemicals, Inc. (JP) | 2010-09-08 | — | — | EP | disclosed |
| US-6255417-B1 | PREPARING OLEFINIC POLYMER IN ALIPHATIC HYDROCARBON SOLVENT USING MODIFIED METALLOCENE CATALYST HAVING AT LEAST ONE ALKYL SUBSTITUENT TO INCREASE SOLUBILITY IN SOLVENT, THEREBY INCREASING ACTIVITY | LG CHEMICAL LTD. (KR) | 2001-07-03 | — | — | US | disclosed |
| EP-0863920-B1 | PROCESS FOR THE PREPARATION OF OLEFINIC POLYMERS USING METALLOCENE CATALYST | LG CHEMICAL LTD (KR) | 2001-02-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120049391-A1 | PROCESS FOR PREPARING ORGANIC ALKALI METAL COMPOUND AND ORGANIC TRANSITION METAL COMPOUND | NHP2, SSRP1, RER1 | CYP17A1 1181/4885ALDH1A1 2243/4885MAPT 3366/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.