SCHEMBL724475

SCHEMBL724475

CC(Cc1ccc2c(c1)Cc1ccccc1-2)C1=CC=CC1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.45
ALDH1A1 P00352 2/20 0.45
ATM Q13315 1/20 0.45
NPSR1 Q6W5P4 1/20 0.45
NPC1 O15118 3/20 0.41
RAB9A P51151 3/20 0.41
CYP1A2 P05177 3/20 0.41
SMN1; SMN2 Q16637 2/20 0.41
CYP3A4 P08684 2/20 0.41
CYP2D6 P10635 1/20 0.41
CYP2C9 P11712 1/20 0.41
CYP2C19 P33261 1/20 0.41
HSD17B10 Q99714 1/20 0.41
TP53 P04637 1/20 0.41
MAPK1 P28482 1/20 0.41
CYP17A1 P05093 2/20 0.40
KDM4E B2RXH2 1/20 0.39
LMNA P02545 1/20 0.39
MAPT P10636 1/20 0.39
HPGD P15428 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6675359 0.99 TSHR (0.44) TSHRALDH1A1ATMNPSR1NPC1
SCHEMBL8151884 0.80 TSHR (0.43) TSHRALDH1A1ATMNPSR1NPC1
SCHEMBL22310130 0.77 TSHR (0.54) TSHRALDH1A1ATMNPSR1NPC1
SCHEMBL723322 0.77 CYP17A1 (0.47) TSHRALDH1A1ATMNPSR1NPC1
SCHEMBL7080010 0.77 ALDH1A1 (0.41) TSHRALDH1A1ATMNPSR1NPC1
SCHEMBL8151284 0.77 TSHR (0.41) TSHRALDH1A1ATMNPSR1NPC1
SCHEMBL27525074 0.76 PNMT (0.49) NPC1RAB9ACYP1A2CYP3A4CYP2D6
Hydrochloric Acid SCHEMBL7605843 0.74 PNMT (0.47) NPC1RAB9A
SCHEMBL8161784 0.73 TSHR (0.51) TSHRALDH1A1ATMNPSR1NPC1
SCHEMBL5357579 0.70 ALDH1A1 (0.59) TSHRALDH1A1ATMNPSR1NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5670681-A Process for preparing a carbon-bridged biscyclopentadiene compound HOECHST AKTIENGESELLSCHAFT (DE) 1997-09-23 US claimed
EP-0548274-B1 IONIC CATALYST FOR THE PRODUCTION OF POLY-ALPHA-OLEFINS OF CONTROLLED TACTICITY EXXON CHEMICAL PATENTS INC (US) 1996-02-28 EP claimed
EP-0548274-A1 IONIC CATALYST FOR THE PRODUCTION OF POLY--g(a)-OLEFINS OF CONTROLLED TACTICITY. EXXON CHEMICAL PATENTS INC (US) 1993-06-30 EP claimed
WO-1992005208-A1 IONIC CATALYST FOR THE PRODUCTION OF POLY-α-OLEFINS OF CONTROLLED TACTICITY EXXON CHEMICAL PATENTS INC. (US) 1992-04-02 WO claimed
EP-2226326-B1 METHOD FOR PRODUCING ORGANIC ALKALI METAL COMPOUND AND METHOD FOR PRODUCING ORGANIC TRANSITION METAL COMPOUND MITSUI CHEMICALS INC (JP) 2016-02-17 EP disclosed
EP-2734554-A1 METHOD FOR PREPARING DIALKYL MAGNESIUM COMPOUNDS BY ETHYLENE POLYMERISATION AND USES THEREOF Universite De Lille 1 Sciences Et Technologies (FR) 2014-05-28 EP disclosed
US-8409480-B2 Process for preparing organic alkali metal compound and organic transition metal compound MITSUI CHEMICALS, INC. (JP) 2013-04-02 US disclosed
WO-2013014383-A1 METHOD FOR PREPARING DIALKYL MAGNESIUM COMPOUNDS BY ETHYLENE POLYMERISATION AND USES THEREOF UNIVERSITE DE LILLE 1 SCIENCES ET TECHNOLOGIES (FR) 2013-01-31 WO disclosed
US-20120049391-A1 PROCESS FOR PREPARING ORGANIC ALKALI METAL COMPOUND AND ORGANIC TRANSITION METAL COMPOUND MITSUI CHEMICALS, INC. 2012-03-01 US disclosed
EP-2226326-A1 METHOD FOR PRODUCING ORGANIC ALKALI METAL COMPOUND AND METHOD FOR PRODUCING ORGANIC TRANSITION METAL COMPOUND Mitsui Chemicals, Inc. (JP) 2010-09-08 EP disclosed
EP-0963990-B1 PROCESS FOR PRODUCING CYCLOPENTADIENYL METAL SALTS AND PROCESS FOR PRODUCING CYCLOPENTADIENE DERIVATIVES BY UTILIZING THE SAME SUMITOMO CHEMICAL CO (JP) 2004-10-06 EP disclosed
US-6197990-B1 REACTING CYCLOPENTADIENE AND METAL HYDRIDE IN PRESENCE OF AMINE COMPOUND SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2001-03-06 US disclosed
US-5331054-A Blends; heat sealing film for packaging MITSUBISHI PETROCHEMICAL COMPANY, LTD. (JP) 1994-07-19 US disclosed
EP-0574258-A2 Process for producing alpha-olefin polymers MITSUBISHI CHEMICAL CORPORATION (JP) 1993-12-15 EP disclosed
US-5252677-A Epoxy, hydroxy or sulfonic acid end groups MITSUBISHI PETROCHEMICAL COMPANY LIMITED (JP) 1993-10-12 US disclosed
US-5225501-A Transition metal compound and alumoxane catalyst MITSUBISHI PETROCHEMICAL COMPANY LIMITED (JP) 1993-07-06 US disclosed
EP-0538749-A1 Propylene copolymer composition MITSUBISHI PETROCHEMICAL CO., LTD. (JP) 1993-04-28 EP disclosed
EP-0512741-A1 Process for producing a propylene random copolymer MITSUBISHI CHEMICAL CORPORATION (JP) 1992-11-11 EP disclosed
EP-0498675-A2 Production of alpha-olefin polymers MITSUBISHI CHEMICAL CORPORATION (JP) 1992-08-12 EP disclosed
EP-0487278-A2 Functionalized olefin polymers MITSUBISHI CHEMICAL CORPORATION (JP) 1992-05-27 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120049391-A1 PROCESS FOR PREPARING ORGANIC ALKALI METAL COMPOUND AND ORGANIC TRANSITION METAL COMPOUND NHP2, SSRP1, RER1 TSHR 1205/4885ALDH1A1 2243/4885ATM 2698/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.