Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | PLAU | P00749 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.41 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.41 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.41 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16364773 | 0.86 | SMN1; SMN2 (0.50) | ADORA2ATDP1PLAURAB9ANPC1 | |
| SCHEMBL29796455 | 0.86 | SMN1; SMN2 (0.50) | ADORA2ATDP1PLAURAB9ANPC1 | |
| SCHEMBL534151 | 0.85 | MAPT (0.48) | ADORA2ATDP1PLAURAB9ANPC1 | |
| SCHEMBL16320490 | 0.83 | SYK (0.44) | ADORA2ATDP1PLAURAB9ANPC1 | |
| SCHEMBL21455719 | 0.83 | MTNR1A (0.48) | ADORA2ATDP1PLAURAB9ANPC1 | |
| SCHEMBL932150 | 0.82 | MAPT (0.58) | TDP1RAB9ATP53SMN1; SMN2L3MBTL1 | |
| SCHEMBL506497 | 0.80 | ALDH1A1 (0.55) | ADORA2APLAURAB9ANPC1TP53 | |
| Hydrochloric Acid SCHEMBL11095592 | 0.78 | ALDH1A1 (0.53) | ADORA2APLAURAB9ANPC1TP53 | |
| SCHEMBL7235859 | 0.78 | CYP3A4 (0.42) | CYP3A4TDP1RAB9ASMN1; SMN2NFE2L2 | |
| SCHEMBL17061218 | 0.77 | LMNA (0.53) | ADORA2ARAB9ASMN1; SMN2POLBL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112279805-B | Process for preparing 1- (3-methoxypyridin-2-yl) -2-propanone | 浙江金伯士药业有限公司 | 2022-03-22 | — | — | CN | claimed |
| CN-112279805-A | Process for preparing 1- (3-methoxypyridin-2-yl) -2-propanone | 浙江金伯士药业有限公司 | 2021-01-29 | — | — | CN | claimed |
| CN-1651428-A | Preparation method of hydrobromic acid antifebrile dichroanone | SHANGHAI YINNUO BIOCHEMICAL SC (CN) | 2005-08-10 | — | — | CN | claimed |
| US-20230192614-A1 | METHOD FOR PREPARATION OF TRANS-N-BENZYLOXYCARBONYL-(3-HYDROXY-2-PIPERIDINYL)-2-PROPANONE AS INTERMEDIATE OF HALOFUGINONE | CHENGDA PHARMACEUTICALS CO., LTD. (CN) | 2023-06-22 | — | — | US | disclosed |
| WO-2023065610-A1 | PREPARATION METHOD FOR HALOFUGINONE INTERMEDIATE TRANS-N-BENZYLOXYCARBONYL-(3-HYDROXY-2-PIPERIDINYL)-2-ACETONE | 诚达药业股份有限公司 | 2023-04-27 | — | — | WO | disclosed |
| CN-112279805-B | Process for preparing 1- (3-methoxypyridin-2-yl) -2-propanone | 浙江金伯士药业有限公司 | 2022-03-22 | — | — | CN | disclosed |
| CN-112279805-B | Process for preparing 1- (3-methoxypyridin-2-yl) -2-propanone | 浙江金伯士药业有限公司 | 2022-03-22 | — | — | CN | disclosed |
| CN-112279805-A | Process for preparing 1- (3-methoxypyridin-2-yl) -2-propanone | 浙江金伯士药业有限公司 | 2021-01-29 | — | — | CN | disclosed |
| CN-112279805-A | Process for preparing 1- (3-methoxypyridin-2-yl) -2-propanone | 浙江金伯士药业有限公司 | 2021-01-29 | — | — | CN | disclosed |
| US-9714234-B2 | Carbazole carboxamide compounds | BRISTOL-MYERS SQUIBB COMPANY (US) | 2017-07-25 | — | — | US | disclosed |
| US-20160200710-A1 | CARBAZOLE CARBOXAMIDE COMPOUNDS | BRISTOL MYERS SQUIBB CO (US) | 2016-07-14 | — | — | US | disclosed |
| CN-103664741-B | Preparation method of 2-acetonyl-3-methoxypiperidine | GUANGZHOU WISDOM BIO TECHNOLOGY CO LTD | 2015-04-29 | — | — | CN | disclosed |
| CN-1304391-C | Preparation method of hydrobromic acid antifebrile dichroanone | SHANGHAI YINNUO BIOCHEMICAL SC (CN) | 2007-03-14 | — | — | CN | disclosed |
| CN-1651428-A | Preparation method of hydrobromic acid antifebrile dichroanone | SHANGHAI YINNUO BIOCHEMICAL SC (CN) | 2005-08-10 | — | — | CN | disclosed |
| US-6521643-B1 | Prevention and/or treatment of nitric oxide synthasey medi-ated diseases such as adult respiratory distress syndrome, myocarditis, synovitis, septic shock, diabetes, ulcerative colitis, cerebral infarction, osteoarthritis | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2003-02-18 | — | — | US | disclosed |
| EP-1157022-A1 | PYRIDINE COMPOUNDS AND THEIR PHARMACEUTICAL USE | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-11-28 | — | — | EP | disclosed |
| WO-2000049015-A1 | PYRIDINE COMPOUNDS AND THEIR PHARMACEUTICAL USE | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-08-24 | — | — | WO | disclosed |
| US-4797486-A | ANTIPROTOZOA AGENTS | PFIZER INC. (US) | 1989-01-10 | — | — | US | disclosed |
| US-4725599-A | POULTRY | PFIZER INC. (US) | 1988-02-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160200710-A1 | CARBAZOLE CARBOXAMIDE COMPOUNDS | BTK, CNKSR1, SYK | ADORA2A 3343/4885CYP3A4 2551/4885TDP1 1084/4885 |
| US-20230192614-A1 | METHOD FOR PREPARATION OF TRANS-N-BENZYLOXYCARBONYL-(3-HYDROXY-2-PIPERIDINYL)-2-PROPANONE AS INTERMEDIATE OF HALOFUGINONE | TALDO1, RPL22, RPS20 | ADORA2A 2060/4885CYP3A4 955/4885TDP1 4053/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.