SCHEMBL723391

SCHEMBL723391

CCC(CCC(=O)O)C(C)=O

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FOLH1 Q04609 11/20 0.48
GABRP O00591 2/20 0.44
GABRD O14764 2/20 0.44
GABRA1 P14867 2/20 0.44
GABRB1 P18505 2/20 0.44
GABRG2 P18507 2/20 0.44
GABRB3 P28472 2/20 0.44
GABRA5 P31644 2/20 0.44
GABRA3 P34903 2/20 0.44
GABRA2 P47869 2/20 0.44
GABRB2 P47870 2/20 0.44
GABRA4 P48169 2/20 0.44
GABRE P78334 2/20 0.44
GABRA6 Q16445 2/20 0.44
GABRG1 Q8N1C3 2/20 0.44
GABRG3 Q99928 2/20 0.44
GABRQ Q9UN88 2/20 0.44
CYP1A2 P05177 1/20 0.44
GRM3 Q14832 2/20 0.42
NAALAD2 Q9Y3Q0 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10533971 0.87 FOLH1 (0.54) FOLH1GABRPGABRDGABRA1GABRB1
SCHEMBL11586967 0.84 HDAC1 (0.52) FOLH1GABRPGABRDGABRA1GABRB1
Acetic Acid SCHEMBL9401153 0.84 FOLH1 (0.58) FOLH1GRM3NAALAD2
SCHEMBL25853752 0.83 ALDH1A1 (0.43) HDAC1HDAC2HDAC8
SCHEMBL1722576 0.83 FOLH1 (0.62) FOLH1CYP1A2GRM3NAALAD2
SCHEMBL15679634 0.81 FOLH1 (0.48) FOLH1GABRPGABRDGABRA1GABRB1
SCHEMBL29103756 0.81 FOLH1 (0.60) FOLH1CYP1A2GRM3NAALAD2
Hydrochloric Acid SCHEMBL5841423 0.81 FOLH1 (0.60) FOLH1CYP1A2GRM3NAALAD2
SCHEMBL11585771 0.80 CA2 (0.52) FOLH1
SCHEMBL13768900 0.79 FOLH1 (0.46) FOLH1GABRPGABRDGABRA1GABRB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8822127-B2 Photosensitive resin composition for black matrix LG CHEM, LTD. (KR) 2014-09-02 US claimed
US-20110151379-A1 BLACK MATRIX COMPOSITION WITH HIGH LIGHT-SHIELDING AND IMPROVED ADHESION PROPERTIES LG CHEM, LTD. (KR) 2011-06-23 US claimed
US-20030073654-A1 Stabilized transient gene expression GENESPAN CORPORATION 2003-04-17 US claimed
EP-1084237-A1 STABILIZED TRANSIENT GENE EXPRESSION Genespan Corporation (US) 2001-03-21 EP claimed
US-6146847-A INTRODUCING FOREIGN DNA INTO CELL; CONTACTING BEFORE, DURING, OR AFTER WITH BIOCOMPATIBLE EXPRESSION ENHANCING AGENT WHICH IS NOT BUTYRATE OR BUTYRIC ACID; MAINTAINING IN NON-SELECTIVE MEDIUM; AFTER 5 DAYS, DETECTING FOREIGN PROTEIN GENESPAN CORPORATION (US) 2000-11-14 US claimed
WO-1999064578-A1 STABILIZED TRANSIENT GENE EXPRESSION GENESPAN CORPORATION (US) 1999-12-16 WO claimed
CN-112899246-B Aldehyde ketone reductase KmAKR mutant and application thereof in catalytic synthesis of chiral alcohol 浙江工业大学 2022-06-21 CN disclosed
CN-112661639-A Synthesis method of 4-acetylbutyrate compound 浙江工业大学 2021-04-16 CN disclosed
CN-104471481-B Photosensitive resin composition and touch panel or display device including bezel pattern prepared by using the same 株式会社LG化学 2019-04-19 CN disclosed
EP-2609426-B1 FLUORESCENCE LABELING REAGENTS AND USES THEREOF TEXAS A & M UNIV SYS (US) 2018-12-19 EP disclosed
CN-104335120-B Photosensitive resin composition, pattern formed using the same, and display panel including the same 株式会社LG化学 2018-04-03 CN disclosed
US-9896522-B2 Solid phase fluorescence labeling reagents and uses thereof THE TEXAS A&M UNIVERSITY SYSTEM (US) 2018-02-20 US disclosed
US-9826223-B2 Stereoscopic image display device including light shielding pattern formed using phase change ink composition LG CHEM, LTD. (KR) 2017-11-21 US disclosed
EP-1420021-A1 DNA Methyltransferase inhibitors The Penn State Research Foundation (US) 2004-05-19 EP disclosed
EP-1181291-A2 DNA METHYLTRANSFERASE INHIBITORS THE PENN STATE RESEARCH FOUNDATION (US) 2002-02-27 EP disclosed
WO-2000075142-A2 DNA METHYLTRANSFERASE INHIBITORS THE PENN STATE RESEARCH FOUNDATION (US) 2000-12-14 WO disclosed
EP-0868443-B1 INTERNALLY BLOCKED POLYAMINE CROSSLINKERS AND COATING COMPOSITIONS CONTAINING THE SAME AKZO NOBEL NV (NL) 2000-08-02 EP disclosed
US-6077929-A Internally blocked polyamine crosslinkers and coating compositions containing the same AKZO NOBEL N.V. (NL) 2000-06-20 US disclosed
EP-0868443-A1 INTERNALLY BLOCKED POLYAMINE CROSSLINKERS AND COATING COMPOSITIONS CONTAINING THE SAME Akzo Nobel N.V. (NL) 1998-10-07 EP disclosed
WO-1997013795-A1 INTERNALLY BLOCKED POLYAMINE CROSSLINKERS AND COATING COMPOSITIONS CONTAINING THE SAME AKZO NOBEL N.V. (NL) 1997-04-17 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030073654-A1 Stabilized transient gene expression MYC, FIBP, SLC2A8 FOLH1 1701/4885GABRP 4476/4885GABRD 3366/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.