Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 6/20 | 0.39 |
| ▸ | CA1 | P00915 | 4/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.36 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.34 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28192721 | 0.86 | CA2 (0.45) | ALDH1A1TSHRUSP2CA2CA1 | |
| SCHEMBL28193296 | 0.83 | HDAC7 (0.48) | ALDH1A1TSHRCA2CA1MAPK1 | |
| SCHEMBL723389 | 0.83 | CA2 (0.58) | ALDH1A1CA2MAPK1TDP1LMNA | |
| SCHEMBL723391 | 0.83 | FOLH1 (0.48) | HDAC8HDAC1HDAC2 | |
| SCHEMBL28142687 | 0.81 | CA2 (0.59) | ALDH1A1TSHRUSP2CA2CA1 | |
| SCHEMBL28753824 | 0.81 | ALDH1A1 (0.39) | ALDH1A1TSHRUSP2CA2CA1 | |
| SCHEMBL28048852 | 0.81 | TSHR (0.38) | TSHRUSP2CA2CA1MAPK1 | |
| SCHEMBL28753825 | 0.81 | ALDH1A1 (0.39) | ALDH1A1TSHRUSP2CA2CA1 | |
| SCHEMBL27543202 | 0.81 | TSHR (0.38) | TSHRUSP2CA2CA1MAPK1 | |
| SCHEMBL8722957 | 0.81 | CA2 (0.43) | TSHRUSP2CA2CA1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101600681-B | Process for the reductive amination of aldehydes and ketones | DOW GLOBAL TECHNOLOGIES INC | 2013-09-18 | — | — | CN | claimed |
| US-20230322989-A1 | BONDING DISSIMILAR POLYMER NETWORKS IN VARIOUS MANUFACTURING PROCESSES | NATIONAL SCIENCE FOUNDATION | 2023-10-12 | — | — | US | disclosed |
| US-11702495-B2 | Bonding dissimilar polymer networks in various manufacturing processes | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2023-07-18 | — | — | US | disclosed |
| US-9839694-B2 | Reduction of endotoxins from polyanionic polymer conjugates | NITTO DENKO CORPORATION (JP) | 2017-12-12 | — | — | US | disclosed |
| CN-101600681-B | Process for the reductive amination of aldehydes and ketones | DOW GLOBAL TECHNOLOGIES INC | 2013-09-18 | — | — | CN | disclosed |
| US-8318795-B2 | Antioxidant polymers containing [1,2]-dithiolane moieties and uses thereof | CEDARS-SINAI MEDICAL CENTER (US) | 2012-11-27 | — | — | US | disclosed |
| CN-101213167-B | Process for reductive amination of aldehydes and ketones by formation of macrocyclic polyimine intermediates | DOW GLOBAL TECHNOLOGIES INC | 2012-05-23 | — | — | CN | disclosed |
| CN-101600681-A | The reduction amination method of aldehyde and ketone | DOW GLOBAL TECHNOLOGIES INC (US) | 2009-12-09 | — | — | CN | disclosed |
| CN-101213167-A | Process for reductive amination of aldehydes and ketones by formation of macrocyclic polyimine intermediates | DOW GLOBAL TECHNOLOGIES INC (US) | 2008-07-02 | — | — | CN | disclosed |