SCHEMBL723476

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL723189	0.91	ALDH1A1 (0.54)	RNF4ALDH1A1HTTSMN1; SMN2MAPT
	SCHEMBL722298	0.90	MITF (0.56)	RNF4ALDH1A1HTTSMN1; SMN2MAPT
	SCHEMBL723784	0.90	ALDH1A1 (0.53)	RNF4ALDH1A1HTTSMN1; SMN2MAPT
	SCHEMBL724014	0.90	NPC1 (0.47)	ALDH1A1MAPTNPC1RAB9APDGFRA
	SCHEMBL721787	0.84	TGM2 (0.52)	PDGFRAKDRKITAXLMAP2K7
	SCHEMBL723733	0.83	ALDH1A1 (0.46)	RNF4ALDH1A1HTTSMN1; SMN2MAPT
	SCHEMBL723499	0.81	HTT (0.43)	RNF4ALDH1A1HTTSMN1; SMN2MITF
	SCHEMBL723378	0.81	CYP3A4 (0.47)	ALDH1A1HTTSMN1; SMN2MAPTLMNA
	SCHEMBL723786	0.80	CYP3A4 (0.48)	ALDH1A1SMN1; SMN2MAPTLMNACYP1A2
	SCHEMBL723570	0.80	CYP3A4 (0.46)	ALDH1A1HTTSMN1; SMN2MAPTLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.