Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 12/20 | 0.56 |
| ▸ | MTNR1B | P49286 | 12/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 7/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7228935 | 1.00 | MTNR1A (0.56) | MTNR1AMTNR1BTP53HTR2CCA12 | |
| SCHEMBL7235756 | 0.83 | MTNR1A (0.54) | MTNR1AMTNR1BTP53 | |
| SCHEMBL7235758 | 0.83 | MTNR1A (0.54) | MTNR1AMTNR1BTP53 | |
| SCHEMBL7011236 | 0.80 | MTNR1A (0.61) | MTNR1AMTNR1BTP53HTR2CCA12 | |
| SCHEMBL7238438 | 0.80 | MTNR1A (0.61) | MTNR1AMTNR1BTP53HTR2CCA12 | |
| SCHEMBL7236340 | 0.78 | MTNR1A (0.56) | MTNR1AMTNR1B | |
| SCHEMBL7236345 | 0.78 | MTNR1A (0.56) | MTNR1AMTNR1B | |
| SCHEMBL7099044 | 0.75 | MTNR1A (0.54) | MTNR1AMTNR1BTP53HTR2CCA12 | |
| Ammonia Solution, Strong SCHEMBL27511408 | 0.74 | MTNR1A (0.53) | MTNR1AMTNR1BTP53HTR2CCA12 | |
| SCHEMBL7230881 | 0.72 | MTNR1A (1.00) | MTNR1AMTNR1BHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1216856-C | Novel cyclocompound having cycloalkylene chain, prepn. method and pharmaceutical compositions contg. same | ADIR (FR) | 2005-08-31 | — | — | CN | disclosed |
| US-6583319-B1 | Treating or preventing melatoninergic disorders | LES LABORATOIRES SERVIER (FR) | 2003-06-24 | — | — | US | disclosed |