Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 9/20 | 0.56 |
| ▸ | MTNR1B | P49286 | 5/20 | 0.56 |
| ▸ | HTR2A | P28223 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.40 |
| ▸ | MYB | P10242 | 1/20 | 0.37 |
| ▸ | DPP4 | P27487 | 4/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7236340 | 1.00 | MTNR1A (0.56) | MTNR1AMTNR1BHTR2ACYP1A2CYP2A6 | |
| SCHEMBL7238729 | 0.81 | MTNR1A (0.42) | MTNR1AMTNR1BCYP1A2CYP2A6 | |
| SCHEMBL7238732 | 0.81 | MTNR1A (0.42) | MTNR1AMTNR1BCYP1A2CYP2A6 | |
| SCHEMBL7012397 | 0.80 | MTNR1A (0.61) | MTNR1AMTNR1BHTR2ACYP1A2CYP2A6 | |
| SCHEMBL7236200 | 0.80 | MTNR1A (0.61) | MTNR1AMTNR1BHTR2ACYP1A2CYP2A6 | |
| SCHEMBL7228935 | 0.78 | MTNR1A (0.56) | MTNR1AMTNR1B | |
| SCHEMBL7228928 | 0.78 | MTNR1A (0.56) | MTNR1AMTNR1B | |
| SCHEMBL7102201 | 0.75 | MTNR1A (0.64) | MTNR1AMTNR1BHTR2ACYP1A2CYP2A6 | |
| SCHEMBL7231435 | 0.75 | MTNR1A (0.65) | MTNR1AMTNR1B | |
| SCHEMBL7229523 | 0.75 | MTNR1A (0.65) | MTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6583319-B1 | Treating or preventing melatoninergic disorders | LES LABORATOIRES SERVIER (FR) | 2003-06-24 | — | — | US | disclosed |