Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 3/20 | 0.32 |
| ▸ | DNM2 | P50570 | 2/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5824071 | 0.80 | DNM1 (0.39) | DNM1DNM2KCNH2CYP2D6TSHR | |
| SCHEMBL7236348 | 0.78 | DNM1 (0.43) | DNM1DNM2KCNH2CYP2D6TSHR | |
| SCHEMBL10866838 | 0.77 | GBA1 (0.32) | DNM1DNM2CA12CA1CA2 | |
| SCHEMBL18641556 | 0.76 | DNM1 (0.40) | DNM1DNM2KCNH2CYP2D6ALDH1A1 | |
| SCHEMBL3182836 | 0.74 | HTT (0.41) | DNM1DNM2CYP2D6ALDH1A1TSHR | |
| SCHEMBL4721367 | 0.72 | LATS1 (0.37) | DNM1DNM2CYP2D6ALDH1A1 | |
| SCHEMBL7978876 | 0.72 | ADH1C (0.38) | — | |
| SCHEMBL4765553 | 0.71 | SMN1; SMN2 (0.39) | DNM2CYP2D6TSHR | |
| SCHEMBL4723666 | 0.71 | CRHR1 (0.42) | DNM2ALDH1A1TSHR | |
| SCHEMBL4723984 | 0.69 | MAPT (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5561131-A | INCREASING THE WOOL GROWTH BY ADMINISTERING AN ANTIPROTOZOA AGENT TO SHEEP | MALLINCKRODT VETERINARY, INC. (US) | 1996-10-01 | — | — | US | disclosed |
| EP-0661976-A1 | DEFAUNATION METHOD | MALLINCKRODT VETERINARY LIMITED (AU) | 1995-07-12 | — | — | EP | disclosed |
| EP-0661976-A4 | DEFAUNATION METHOD. | MALLINCKRODT VETERINARY LTD (AU) | 1994-07-20 | — | — | EP | disclosed |
| WO-1993002680-A1 | DEFAUNATION METHOD | PITMAN-MOORE AUSTRALIA LIMITED (AU) | 1993-02-18 | — | — | WO | disclosed |