Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.60 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.60 |
| ▸ | TSHR | P16473 | 3/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1223375 | 0.88 | HPGD (0.76) | HPGDALDH1A1TSHRSMN1; SMN2POLB | |
| SCHEMBL7242265 | 0.81 | HPGD (0.73) | HPGDALDH1A1ADRB2TSHRSMN1; SMN2 | |
| SCHEMBL7235196 | 0.81 | ALDH1A1 (0.61) | HPGDALDH1A1SMN1; SMN2POLBHTT | |
| SCHEMBL7235193 | 0.81 | ALDH1A1 (0.61) | HPGDALDH1A1SMN1; SMN2POLBHTT | |
| SCHEMBL7232365 | 0.79 | ALDH1A1 (0.55) | HPGDALDH1A1ADRB2TSHRSMN1; SMN2 | |
| SCHEMBL7234470 | 0.77 | NAAA (0.55) | HPGDALDH1A1NPC1RAB9A | |
| SCHEMBL13804124 | 0.77 | ALDH1A1 (0.61) | HPGDALDH1A1SMN1; SMN2POLBNPC1 | |
| SCHEMBL13468069 | 0.77 | ALDH1A1 (0.67) | HPGDALDH1A1SMN1; SMN2POLBMEN1 | |
| SCHEMBL16442058 | 0.77 | ALDH1A1 (0.64) | HPGDALDH1A1SMN1; SMN2POLB | |
| SCHEMBL1520334 | 0.77 | ALDH1A1 (0.64) | HPGDALDH1A1SMN1; SMN2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6664271-B1 | Amide, carbamate and uredo derivatives of 3-piperidine-carboxylic acid or ester; protecting against infection by such as escherichia coli and/or actinobacillus pleuropneumoniae | ELI LILLY AND COMPANY | 2003-12-16 | — | — | US | claimed |
| US-6664271-B1 | Amide, carbamate and uredo derivatives of 3-piperidine-carboxylic acid or ester; protecting against infection by such as escherichia coli and/or actinobacillus pleuropneumoniae | ELI LILLY AND COMPANY | 2003-12-16 | — | — | US | disclosed |