Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSPO | P30536 | 1/20 | 0.47 |
| ▸ | TACR1 | P25103 | 5/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.45 |
| ▸ | CXCR2 | P25025 | 4/20 | 0.45 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.43 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7238513 | 0.92 | TSPO (0.56) | TSPOTACR1KDM4EALDH1A1CYP1A2 | |
| SCHEMBL6810265 | 0.89 | CXCR2 (0.56) | CXCR2CYP2C9 | |
| SCHEMBL6810526 | 0.89 | CXCR2 (0.47) | CXCR2MTNR1AMTNR1BHDAC1CYP2C9 | |
| SCHEMBL28750238 | 0.88 | CXCR2 (0.41) | TSPOKDM4EALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL6365302 | 0.86 | PPARG (0.49) | TSPOTACR1KDM4EALDH1A1CYP1A2 | |
| SCHEMBL7241810 | 0.86 | CXCR2 (0.56) | TSPOTACR1CXCR2CYP2C9 | |
| SCHEMBL7238595 | 0.86 | CXCR2 (0.53) | TSPOTACR1KDM4EALDH1A1CYP1A2 | |
| SCHEMBL7232831 | 0.84 | TACR1 (0.45) | TSPOTACR1KDM4EALDH1A1CYP1A2 | |
| SCHEMBL7232861 | 0.84 | TSPO (0.47) | TSPOTACR1KDM4EALDH1A1CYP1A2 | |
| SCHEMBL7241409 | 0.84 | TSPO (0.47) | TSPOTACR1KDM4EALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040138287-A1 | Novel 5-phenyl-1h-indole derivatives as antagonists of interleukine-8 receptors | LABORATOIRES FOURNIER S.A. (FR) | 2004-07-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040138287-A1 | Novel 5-phenyl-1h-indole derivatives as antagonists of interleukine-8 receptors | CXCL8, IL1RN, CCR8 | TSPO 2510/4885TACR1 187/4885KDM4E 2367/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.