Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 6/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4861276 | 0.86 | ALDH1A1 (0.46) | ALDH1A1 | |
| SCHEMBL7250847 | 0.85 | ALDH1A1 (0.46) | ALDH1A1 | |
| SCHEMBL6141903 | 0.83 | GAA (0.49) | PTGS2PTGS1 | |
| SCHEMBL4859624 | 0.80 | PTGS2 (0.46) | PTGS2PTGS1ALDH1A1 | |
| SCHEMBL6141870 | 0.78 | HTT (0.49) | ALDH1A1 | |
| SCHEMBL14193776 | 0.78 | PTGS2 (0.42) | PTGS2PTGS1ALDH1A1 | |
| SCHEMBL5821095 | 0.76 | CA9 (0.43) | PTGS2PTGS1ALDH1A1 | |
| SCHEMBL4861280 | 0.76 | ALDH1A1 (0.40) | ALDH1A1 | |
| SCHEMBL14193782 | 0.75 | PTGS2 (0.44) | PTGS2PTGS1ALDH1A1 | |
| SCHEMBL14223770 | 0.74 | ALDH1A1 (0.43) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030225075-A1 | Novel pyrimidone derivatives | ORCHID CHEMICALS & PHARMACEUTICALS LIMITED (IN) | 2003-12-04 | — | — | US | claimed |
| US-20030225075-A1 | Novel pyrimidone derivatives | ORCHID CHEMICALS & PHARMACEUTICALS LIMITED (IN) | 2003-12-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030225075-A1 | Novel pyrimidone derivatives | TPMT, TYMP, TYMS | PTGS2 1692/4885PTGS1 1288/4885ALDH1A1 357/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.