SCHEMBL723948

SCHEMBL723948

NOn1cnc2c(S)ncnc21

nearest known ligand 0.34

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
ADORA2A P29274 6/20 0.34
ADORA1 P30542 5/20 0.34
PI4KA P42356 4/20 0.32
PI4K2B Q8TCG2 4/20 0.32
PI4K2A Q9BTU6 4/20 0.32
PI4KB Q9UBF8 4/20 0.32
ADORA2B P29275 2/20 0.32
EGFR P00533 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5490469 0.75 ADORA2A (0.37) ADORA2AADORA1PI4KAPI4K2BPI4K2A
SCHEMBL1683802 0.74 ADORA2A (0.35) ADORA2AADORA1PI4KAPI4K2BPI4K2A
SCHEMBL26348810 0.71 ADORA2A (0.33) ADORA2AADORA1PI4KAPI4K2BPI4K2A
SCHEMBL3857168 0.71 ADORA1 (0.60) ADORA2AADORA1PI4KAPI4K2BPI4K2A
SCHEMBL25325575 0.71 ADORA2A (0.33) ADORA2AADORA1PI4KAPI4K2BPI4K2A
SCHEMBL24409387 0.68 ADORA2A (0.51) ADORA2AADORA1PI4KAPI4K2BPI4K2A
SCHEMBL5403761 0.67 ADORA2A (0.64) ADORA2AADORA1PI4KAPI4K2BPI4K2A
SCHEMBL7041894 0.66 SLC29A1 (0.46) ADORA2AADORA1PI4KAPI4K2BPI4K2A
SCHEMBL11033550 0.66 ADORA2A (0.45) ADORA2AADORA1PI4KAPI4K2BPI4K2A
SCHEMBL11259247 0.64 ADORA2A (0.47) ADORA2AADORA1PI4KAPI4K2BPI4K2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250205467-A1 SYSTEMS AND METHODS FOR THE TREATMENT OF CANCER USING ULTRASOUND DUKE UNIVERSITY 2025-06-26 US disclosed
CN-119136746-A System and method for treating cancer using ultrasound 杜克大学 2024-12-13 CN disclosed
US-11364043-B2 Methods and devices for endovascular therapy CARDIOPROLIFIC INC. (US) 2022-06-21 US disclosed
US-11116528-B2 Methods and devices for endovascular therapy CARDIOPROLIFIC, INC. (US) 2021-09-14 US disclosed
US-11039845-B2 Methods and devices for endovascular therapy CARDIOPROLIFIC INC. (US) 2021-06-22 US disclosed
US-20160367275-A1 METHODS AND DEVICES FOR ENDOVASCULAR THERAPY CARDIOPROLIFIC INC (US) 2016-12-22 US disclosed
US-20160367274-A1 METHODS AND DEVICES FOR ENDOVASCULAR THERAPY CARDIOPROLIFIC INC (US) 2016-12-22 US disclosed
US-20160270806-A1 METHODS AND DEVICES FOR ENDOVASCULAR THERAPY CARDIOPROLIFIC INC (US) 2016-09-22 US disclosed
US-9375223-B2 Methods and devices for endovascular therapy CARDIOPROLIFIC INC. (US) 2016-06-28 US disclosed
US-20140142494-A1 METHODS AND DEVICES FOR ENDOVASCULAR THERAPY CARDIOPROLIFIC INC. 2014-05-22 US disclosed
US-20130023897-A1 Devices and Methods for Endovascular Therapies CARDIOPROLIFIC INC. 2013-01-24 US disclosed
US-20120215099-A1 Methods and Apparatus for Endovascular Ultrasound Delivery CARDIOPROLIFIC INC. 2012-08-23 US disclosed
WO-2012026982-A1 ULTRASOUND-ENHANCED STENOSIS THERAPY WALLACE MICHAEL P (US) 2012-03-01 WO disclosed
US-20110237982-A1 Ultrasound-enhanced stenosis therapy CARDIOPROLIFIC INC. 2011-09-29 US disclosed
US-20110105960-A1 Ultrasound-enhanced Stenosis therapy CARDIOPROLIFIC INC. 2011-05-05 US disclosed
US-20110082396-A1 Ultrasound-enhanced stenosis therapy CARDIOPROLIFIC INC. 2011-04-07 US disclosed
US-20110082534-A1 Ultrasound-enhanced stenosis therapy CARDIOPROLIFIC INC. 2011-04-07 US disclosed
US-20110082414-A1 Ultrasound-enhanced stenosis therapy CARDIOPROLIFIC INC. 2011-04-07 US disclosed
US-20010039952-A1 ULTRASOUND ENHANCED CHEMOTHERAPY WALTER A. HACKER, PH. D 2001-11-15 US disclosed
US-6308714-B1 Ultrasound enhanced chemotherapy CORAJE, INC. 2001-10-30 US disclosed