Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 8/20 | 0.45 |
| ▸ | ADORA1 | P30542 | 4/20 | 0.45 |
| ▸ | PI4KA | P42356 | 3/20 | 0.45 |
| ▸ | PI4K2B | Q8TCG2 | 3/20 | 0.45 |
| ▸ | PI4K2A | Q9BTU6 | 3/20 | 0.45 |
| ▸ | PI4KB | Q9UBF8 | 3/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.42 |
| ▸ | AHCY | P23526 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10387483 | 0.81 | ADORA2A (0.45) | ADORA2AADORA1PI4KAPI4K2BPI4K2A | |
| SCHEMBL11269779 | 0.77 | ADORA2A (0.66) | ADORA2AADORA1PI4KAPI4K2BPI4K2A | |
| SCHEMBL10386729 | 0.73 | TLR7 (0.43) | ADORA2AADORA1PI4KAPI4K2BPI4K2A | |
| SCHEMBL3857168 | 0.73 | ADORA1 (0.60) | ADORA2AADORA1PI4KAPI4K2BPI4K2A | |
| SCHEMBL1683802 | 0.72 | ADORA2A (0.35) | ADORA2AADORA1PI4KAPI4K2BPI4K2A | |
| SCHEMBL8467559 | 0.72 | ADORA2A (0.60) | ADORA2AADORA1CYP1A2CYP2D6MAPK1 | |
| SCHEMBL10387490 | 0.72 | TLR7 (0.44) | ADORA2AADORA1PI4KAPI4K2BPI4K2A | |
| SCHEMBL8921749 | 0.70 | ADORA1 (0.40) | ADORA2AADORA1MAPK1AHCY | |
| SCHEMBL25325575 | 0.69 | ADORA2A (0.33) | ADORA2AADORA1PI4KAPI4K2BPI4K2A | |
| SCHEMBL5490469 | 0.69 | ADORA2A (0.37) | ADORA2AADORA1PI4KAPI4K2BPI4K2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-59134800-A | — | — | None | — | — | JP | disclosed |
| JP-S59134800-A | SILYLALKYLATED 6-MERCAPTOPURINE COMPOUND AND ITS PREPARATION | CHISSO CORP | 1984-08-02 | — | — | JP | disclosed |