Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 7/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 5/20 | 0.33 |
| ▸ | YTHDC1 | Q96MU7 | 1/20 | 0.32 |
| ▸ | PI4KA | P42356 | 3/20 | 0.31 |
| ▸ | PI4K2B | Q8TCG2 | 3/20 | 0.31 |
| ▸ | PI4K2A | Q9BTU6 | 3/20 | 0.31 |
| ▸ | PI4KB | Q9UBF8 | 3/20 | 0.31 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.31 |
| ▸ | GSK3B | P49841 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | AHCY | P23526 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5490469 | 0.75 | ADORA2A (0.37) | ADORA2AADORA1YTHDC1PI4KAPI4K2B | |
| SCHEMBL3857168 | 0.75 | ADORA1 (0.60) | ADORA2AADORA1YTHDC1PI4KAPI4K2B | |
| SCHEMBL11259247 | 0.72 | ADORA2A (0.47) | ADORA2AADORA1PI4KAPI4K2BPI4K2A | |
| SCHEMBL11269779 | 0.72 | ADORA2A (0.66) | ADORA2AADORA1PI4KAPI4K2BPI4K2A | |
| SCHEMBL2116000 | 0.71 | ADORA2A (0.64) | ADORA2AADORA1PI4KAPI4K2BPI4K2A | |
| SCHEMBL723948 | 0.71 | ADORA2A (0.34) | ADORA2AADORA1PI4KAPI4K2BPI4K2A | |
| SCHEMBL11033550 | 0.69 | ADORA2A (0.45) | ADORA2AADORA1PI4KAPI4K2BPI4K2A | |
| SCHEMBL4447617 | 0.68 | GSK3B (0.33) | ADORA2AADORA2BGSK3BAHCY | |
| SCHEMBL463396 | 0.67 | NPC1 (0.52) | ADORA2AADORA1PI4KAPI4K2BPI4K2A | |
| SCHEMBL10387483 | 0.66 | ADORA2A (0.45) | ADORA2AADORA1PI4KAPI4K2BPI4K2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023144235-A1 | METHODS FOR MONITORING AND TREATING WARBURG EFFECT IN PATIENTS WITH PI3K-RELATED DISORDERS | INSERM (Institut National de la Santé et de la Recherche Médicale) (FR) | 2023-08-03 | — | — | WO | disclosed |
| CN-101820762-B | Pyrrolotriazine derivatives for treating cancer through inhibition of aurora kinase | BAYER HEALTHCARE LLC | 2014-07-30 | — | — | CN | disclosed |
| CN-1823070-A | Salinosporamides and methods of use thereof | UNIV CALIFORNIA (US) | 2006-08-23 | — | — | CN | disclosed |