Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 15/20 | 0.74 |
| ▸ | ITGAV | P06756 | 15/20 | 0.74 |
| ▸ | ITGA2B | P08514 | 7/20 | 0.74 |
| ▸ | CASP1 | P29466 | 1/20 | 0.45 |
| ▸ | KYNU | Q16719 | 1/20 | 0.43 |
| ▸ | CTSL | P07711 | 1/20 | 0.42 |
| ▸ | CTSB | P07858 | 1/20 | 0.42 |
| ▸ | CTSS | P25774 | 1/20 | 0.42 |
| ▸ | CTSK | P43235 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | PPARA | Q07869 | 1/20 | 0.42 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.42 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6016434 | 0.90 | ITGB3 (0.61) | ITGB3ITGAVITGA2BCASP1KYNU | |
| SCHEMBL6016218 | 0.85 | ITGB3 (0.75) | ITGB3ITGAVITGA2BCASP1 | |
| SCHEMBL6016219 | 0.83 | ITGB3 (0.60) | ITGB3ITGAVITGA2BCASP1CTSL | |
| SCHEMBL3370106 | 0.82 | CASP1 (0.53) | ITGB3ITGAVITGA2BCASP1KYNU | |
| SCHEMBL5626356 | 0.81 | ITGB3 (0.63) | ITGB3ITGAVITGA2BKYNUCTSL | |
| SCHEMBL5626363 | 0.81 | ITGB3 (0.63) | ITGB3ITGAVITGA2BKYNUCTSL | |
| SCHEMBL6016166 | 0.79 | ITGB3 (1.00) | ITGB3ITGAVITGA2B | |
| SCHEMBL6016256 | 0.78 | ITGB3 (0.62) | ITGB3ITGAVITGA2BCASP1CTSL | |
| SCHEMBL7370216 | 0.76 | CTSK (0.57) | ITGB3ITGAVKYNUCTSLCTSB | |
| SCHEMBL7370220 | 0.76 | CTSK (0.57) | ITGB3ITGAVKYNUCTSLCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6566366-B1 | For therapy of tumor growth, osteoporosis, inflammation and cardiovascular disorders | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2003-05-20 | — | — | US | disclosed |