Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.56 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.56 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.56 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 4/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | KIF11 | P52732 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29398386 | 1.00 | ALDH1A1 (0.56) | ALDH1A1CYP3A4HPGDALOX15TSHR | |
| SCHEMBL7039417 | 0.87 | ALDH1A1 (0.51) | ALDH1A1CYP3A4HPGDALOX15TSHR | |
| SCHEMBL28840504 | 0.87 | ALDH1A1 (0.56) | ALDH1A1CYP3A4HPGDALOX15TSHR | |
| SCHEMBL1998640 | 0.85 | CYP3A4 (0.52) | ALDH1A1CYP3A4HPGDALOX15TSHR | |
| SCHEMBL29942185 | 0.84 | ALDH1A1 (0.60) | ALDH1A1CYP3A4HPGDALOX15TSHR | |
| SCHEMBL7240751 | 0.84 | ALDH1A1 (0.60) | ALDH1A1CYP3A4HPGDALOX15TSHR | |
| SCHEMBL8187684 | 0.83 | ALDH1A1 (0.55) | ALDH1A1CYP3A4HPGDALOX15TSHR | |
| SCHEMBL28090702 | 0.82 | MAPK1 (0.47) | ALDH1A1CYP3A4HPGDALOX15TSHR | |
| SCHEMBL11668743 | 0.81 | ALDH1A1 (0.56) | ALDH1A1CYP3A4HPGDALOX15TSHR | |
| SCHEMBL2158306 | 0.81 | ALDH1A1 (0.56) | ALDH1A1CYP3A4HPGDALOX15TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8952083-B2 | Fluorocopolymer composition and its production process | ASAHI GLASS COMPANY, LIMITED (JP) | 2015-02-10 | — | — | US | claimed |
| EP-1468983-B1 | PROCESS FOR PRODUCING 2,5-BIS(TRIFLUOROMETHYL)NITROBENZENE | ASAHI GLASS CO LTD (JP) | 2007-11-21 | — | — | EP | claimed |
| US-6930214-B2 | Process for producing 2,5-bis(trifluoromethyl)nitrobenzene | ASAHI GLASS COMPANY, LIMITED (JP) | 2005-08-16 | — | — | US | claimed |
| US-20040242942-A1 | Process for producing 2,5-bis(trifluoromethyl)nitrobenzene | ASAHI GLASS COMPANY LIMITED (JP) | 2004-12-02 | — | — | US | claimed |
| EP-1468983-A1 | PROCESS FOR PRODUCING 2,5-BIS(TRIFLUOROMETHYL)NITROBENZENE | ASAHI GLASS COMPANY LTD. (JP) | 2004-10-20 | — | — | EP | claimed |
| JP-63159352-A | — | — | None | — | — | JP | disclosed |
| EP-3318561-B1 | HETEROARYL COMPOUNDS AND METHODS OF USE THEREOF | SUNOVION PHARMACEUTICALS INC (US) | 2021-12-22 | — | — | EP | disclosed |
| US-10562916-B2 | Substituted quinoxalines as PDE-10 inhibitors | SUNOVION PHARMACEUTICALS, INC. (US) | 2020-02-18 | — | — | US | disclosed |
| EP-2576540-B1 | HETEROARYL COMPOUNDS AND METHODS OF USE THEREOF | SUNOVION PHARMACEUTICALS INC (US) | 2019-09-04 | — | — | EP | disclosed |
| EP-3318561-A1 | HETEROARYL COMPOUNDS AND METHODS OF USE THEREOF | Sunovion Pharmaceuticals Inc. (US) | 2018-05-09 | — | — | EP | disclosed |
| US-20180037590-A1 | SUBSTITUTED QUINOLINES AS PDE-10 INHIBITORS | SUNOVION PHARMACEUTICALS INC. | 2018-02-08 | — | — | US | disclosed |
| US-20180037590-A1 | SUBSTITUTED QUINOLINES AS PDE-10 INHIBITORS | SUNOVION PHARMACEUTICALS INC. | 2018-02-08 | — | — | US | disclosed |
| US-20040242942-A1 | Process for producing 2,5-bis(trifluoromethyl)nitrobenzene | ASAHI GLASS COMPANY LIMITED (JP) | 2004-12-02 | — | — | US | disclosed |
| US-20040242942-A1 | Process for producing 2,5-bis(trifluoromethyl)nitrobenzene | ASAHI GLASS COMPANY LIMITED (JP) | 2004-12-02 | — | — | US | disclosed |
| US-20040242942-A1 | Process for producing 2,5-bis(trifluoromethyl)nitrobenzene | ASAHI GLASS COMPANY LIMITED (JP) | 2004-12-02 | — | — | US | disclosed |
| EP-1468983-A1 | PROCESS FOR PRODUCING 2,5-BIS(TRIFLUOROMETHYL)NITROBENZENE | ASAHI GLASS COMPANY LTD. (JP) | 2004-10-20 | — | — | EP | disclosed |
| EP-1468983-A1 | PROCESS FOR PRODUCING 2,5-BIS(TRIFLUOROMETHYL)NITROBENZENE | ASAHI GLASS COMPANY LTD. (JP) | 2004-10-20 | — | — | EP | disclosed |
| WO-2003062187-A1 | PROCESS FOR PRODUCING 2,5-BIS(TRIFLUOROMETHYL)NITROBENZENE | ASAHI GLASS COMPANY, LIMITED (JP) | 2003-07-31 | — | — | WO | disclosed |
| CN-1333761-A | Isothiazolecarboxylic acid derivatives | BAYER AGROCHEM KK (JP) | 2002-01-30 | — | — | CN | disclosed |
| JP-S63159352-A | 5-TRICHLOROMETHYL-2-TRIFLUOROMETHYLNITROBENZENE AND 4-TRIFLUOROMETHYL-3-NITROBENZOIC ACID AND PRODUCTION THEREOF | CENTRAL GLASS CO LTD | 1988-07-02 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180037590-A1 | SUBSTITUTED QUINOLINES AS PDE-10 INHIBITORS | PDE10A, PDE2A, PDE3A | ALDH1A1 559/4885CYP3A4 530/4885HPGD 943/4885 |
| US-10562916-B2 | Substituted quinoxalines as PDE-10 inhibitors | PDE4A, PDE2A, PDE9A | ALDH1A1 1140/4885CYP3A4 1077/4885HPGD 98/4885 |
| US-20040242942-A1 | Process for producing 2,5-bis(trifluoromethyl)nitrobenzene | NOS2, NOS1, NOX5 | ALDH1A1 1871/4885CYP3A4 192/4885HPGD 407/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.