SCHEMBL724093

SCHEMBL724093

CC(C)(C)CC(C)(C)c1ccc(O)c(I)c1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SHBG P04278 1/20 0.55
CYP3A4 P08684 4/20 0.54
HIF1A Q16665 2/20 0.54
CYP2D6 P10635 2/20 0.54
ESR1 P03372 3/20 0.49
SMN1; SMN2 Q16637 2/20 0.49
MEN1 O00255 2/20 0.49
AR P10275 2/20 0.49
MAPT P10636 2/20 0.49
KMT2A Q03164 2/20 0.49
USP2 O75604 1/20 0.49
TP53 P04637 1/20 0.49
PGR P06401 1/20 0.49
ADORA3 P0DMS8 1/20 0.49
DRD1 P21728 1/20 0.49
PTGS1 P23219 1/20 0.49
SLC6A2 P23975 1/20 0.49
PDE4A P27815 1/20 0.49
MAPK1 P28482 1/20 0.49
CASP1 P29466 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25454480 0.83 ESR1 (0.46) CYP3A4HIF1ACYP2D6ESR1SMN1; SMN2
SCHEMBL68434 0.82 SHBG (0.61) SHBGCYP3A4HIF1ACYP2D6ESR1
SCHEMBL29457570 0.82 SHBG (0.61) SHBGCYP3A4HIF1ACYP2D6ESR1
SCHEMBL23762849 0.82 SHBG (0.39) SHBGCYP3A4HIF1ACYP2D6ESR1
SCHEMBL9355691 0.81 ESR1 (0.61) SHBGCYP3A4HIF1ACYP2D6ESR1
SCHEMBL7699366 0.81 SHBG (0.59) SHBGCYP3A4HIF1ACYP2D6ESR1
SCHEMBL768277 0.79 SHBG (0.57) SHBGCYP3A4HIF1ACYP2D6ESR1
SCHEMBL340386 0.79 SHBG (0.61) SHBGCYP3A4HIF1ACYP2D6ESR1
SCHEMBL848161 0.78 ALDH1A1 (0.64) CYP2D6ESR1SMN1; SMN2MEN1AR
SCHEMBL31275474 0.78 ESR1 (0.52) CYP3A4CYP2D6ESR1SMN1; SMN2MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 101 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12297311-B2 Biaryl hydroxythiophene group IV transition metal polymerization with chain transfer capability DOW GLOBAL TECHNOLOGIES LLC (US) 2025-05-13 US disclosed
US-20250051495-A1 SUPPORTED CATALYST SYSTEMS CONTAINING A SILOCON BRIDGED, ANTHRACENYL SUBSTITUTED BIS-BIPHENYL-PHENOXY ORGANOMETALLIC COMPOUND FOR MAKING POLYETHYLENE AND POLYETHYLENE COPOLYMER RESINS IN A GAS PHASE POLYMERIZATION REACTOR DOW GLOBAL TECHNOLOGIES LLC (US) 2025-02-13 US disclosed
US-12221508-B2 Biaryl phenoxy group IV transition metal catalysts for olefin polymerization DOW GLOBAL TECHNOLOGIES LLC (US) 2025-02-11 US disclosed
US-20250034292-A1 SUPPORTED CATALYST SYSTEMS CONTAINING A GERMANIUM BRIDGED, ANTHRACENYL SUBSTITUTED BIS-BIPHENYL-PHENOXY ORGANOMETALLIC COMPOUND FOR MAKING POLYETHYLENE AND POLYETHYLENE COPOLYMER RESINS IN A GAS PHASE POLYMERIZATION REACTOR DOW GLOBAL TECHNOLOGIES LLC (US) 2025-01-30 US disclosed
US-20250011478-A1 SUPPORTED CATALYST SYSTEMS CONTAINING A CARBON BRIDGED, ANTHRACENYL SUBSTITUTED BIS-BIPHENYL-PHENOXY ORGANOMETALLIC COMPOUND FOR MAKING POLYETHYLENE AND POLYETHYLENE COPOLYMER RESINS IN A GAS PHASE POLYMERIZATION REACTOR DOW GLOBAL TECHNOLOGIES LLC (US) 2025-01-09 US disclosed
EP-4437013-A1 SUPPORTED CATALYST SYSTEMS CONTAINING A SILOCON BRIDGED, ANTHRACENYL SUBSTITUTED BIS-BIPHENYL-PHENOXY ORGANOMETALLIC COMPOUND FOR MAKING POLYETHYLENE AND POLYETHYLENE COPOLYMER RESINS IN A GAS PHASE POLYMERIZATION REACTOR Dow Global Technologies LLC (US) 2024-10-02 EP disclosed
EP-4437012-A1 SUPPORTED CATALYST SYSTEMS CONTAINING A CARBON BRIDGED, ANTHRACENYL SUBSTITUTED BIS-BIPHENYL-PHENOXY ORGANOMETALLIC COMPOUND FOR MAKING POLYETHYLENE AND POLY ETHYLENE COPOLYMER RESINS IN A GAS PHASE POLYMERIZATION REACTOR Dow Global Technologies LLC (US) 2024-10-02 EP disclosed
CN-118451111-A Supported catalyst system containing silicon-bridged, anthracenyl-substituted bis-biphenyl-phenoxy organometallic compounds for preparing polyethylene and polyethylene copolymer resins in a gas phase polymerization reactor 陶氏环球技术有限责任公司 2024-08-06 CN disclosed
CN-118302457-A Supported catalyst system containing carbon-bridged, anthracenyl-substituted bis-biphenyl-phenoxy organometallic compounds for preparing polyethylene and polyethylene copolymer resins in a gas phase polymerization reactor 陶氏环球技术有限责任公司 2024-07-05 CN disclosed
CN-118302456-A Supported catalyst system containing germanium bridged, anthracenyl substituted bis-biphenyl-phenoxy organometallic compounds for preparing polyethylene and polyethylene copolymer resins in a gas phase polymerization reactor 陶氏环球技术有限责任公司 2024-07-05 CN disclosed
EP-2609123-A1 PROCESS FOR POLYMERIZING A POLYMERIZABLE OLEFIN AND CATALYST THEREFOR Dow Global Technologies LLC (US) 2013-07-03 EP disclosed
US-20130144018-A1 PROCESS FOR POLYMERIZING A POLYMERIZABLE OLEFIN AND CATALYST THEREFOR DOW GLOBAL TECHNOLOGIES LLC (US) 2013-06-06 US disclosed
US-20130144018-A1 PROCESS FOR POLYMERIZING A POLYMERIZABLE OLEFIN AND CATALYST THEREFOR DOW GLOBAL TECHNOLOGIES LLC (US) 2013-06-06 US disclosed
US-20130144018-A1 PROCESS FOR POLYMERIZING A POLYMERIZABLE OLEFIN AND CATALYST THEREFOR DOW GLOBAL TECHNOLOGIES LLC (US) 2013-06-06 US disclosed
EP-2491062-A1 PROCESS FOR SELECTIVELY POLYMERIZING ETHYLENE AND CATALYST THEREFOR Dow Global Technologies LLC (US) 2012-08-29 EP disclosed
WO-2012027448-A1 PROCESS FOR POLYMERIZING A POLYMERIZABLE OLEFIN AND CATALYST THEREFOR DOW GLOBAL TECHNOLOGIES LLC (US) 2012-03-01 WO disclosed
WO-2011146044-A1 PROCESS FOR SELECTIVELY POLYMERIZING ETHYLENE AND CATALYST THEREFOR DOW GLOBAL TECHNOLOGIES LLC (US) 2011-11-24 WO disclosed
WO-2011146291-A1 PROCESS FOR SELECTIVELY POLYMERIZING ETHYLENE AND CATALYST THEREFOR DOW GLOBAL TECHNOLOGIES LLC (US) 2011-11-24 WO disclosed
US-20110282018-A1 PROCESS FOR SELECTIVELY POLYMERIZING ETHYLENE AND CATALYST THEREFOR DOW GLOBAL TECHNOLOGIES LLC 2011-11-17 US disclosed
US-20110282018-A1 PROCESS FOR SELECTIVELY POLYMERIZING ETHYLENE AND CATALYST THEREFOR DOW GLOBAL TECHNOLOGIES LLC 2011-11-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110282018-A1 PROCESS FOR SELECTIVELY POLYMERIZING ETHYLENE AND CATALYST THEREFOR WEE2, NOTUM, WEE1 SHBG 3920/4885CYP3A4 553/4885HIF1A 1106/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.