Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 1/20 | 0.40 |
| ▸ | ANPEP | P15144 | 1/20 | 0.40 |
| ▸ | ENPEP | Q07075 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | THPO | P40225 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 2/20 | 0.37 |
| ▸ | CFD | P00746 | 4/20 | 0.36 |
| ▸ | F11 | P03951 | 4/20 | 0.36 |
| ▸ | TPSB2 | P20231 | 4/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20844633 | 1.00 | TACR1 (0.40) | TACR1ANPEPENPEPCYP2D6CYP1A2 | |
| SCHEMBL3858813 | 0.85 | CFD (0.39) | TACR1ANPEPENPEPCYP2D6CYP1A2 | |
| SCHEMBL20844825 | 0.85 | CFD (0.39) | TACR1ANPEPENPEPCYP2D6CYP1A2 | |
| SCHEMBL11664457 | 0.82 | TACR1 (0.41) | TACR1ANPEPENPEPCYP2D6CYP1A2 | |
| SCHEMBL20844683 | 0.80 | SLC6A4 (0.41) | TACR1ANPEPENPEPCYP2D6CYP1A2 | |
| SCHEMBL20844680 | 0.80 | SLC6A4 (0.41) | TACR1ANPEPENPEPCYP2D6CYP1A2 | |
| SCHEMBL11977597 | 0.80 | SLC6A4 (0.41) | TACR1ANPEPENPEPCYP2D6CYP1A2 | |
| SCHEMBL4321103 | 0.78 | KMT2A (0.55) | TACR1ANPEPENPEPCYP2D6CYP2C19 | |
| SCHEMBL5720959 | 0.78 | KMT2A (0.55) | TACR1ANPEPENPEPCYP2D6CYP2C19 | |
| SCHEMBL30541423 | 0.78 | KMT2A (0.55) | TACR1ANPEPENPEPCYP2D6CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6552192-B1 | Inhibiting cyclin dependent kinase proteins, viruses, and immunostimulation; antimitotic, antiviral, anticancinogenic, antidegenerative, immunosuppressive | USTAU EXPERIMENTALNI BOTANIKY AV-CR (CZ) | 2003-04-22 | — | — | US | disclosed |