SCHEMBL7241920

SCHEMBL7241920

CC(Cc1ccccc1)c1ccc2c3c(ccc2c1)OC(c1ccc(N(C)C)cc1)(c1ccccc1F)C=C3

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
MMP9 P14780 1/20 0.31
PLAUR Q03405 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7253577 0.91 MMP9 (0.35) MMP9PLAUR
Benzene SCHEMBL7241926 0.90 KDM1A (0.34)
SCHEMBL7241102 0.88 GRM2 (0.34)
SCHEMBL7246685 0.85 RORC (0.36)
SCHEMBL4670918 0.83
Benzene SCHEMBL7253583 0.79 KDM1A (0.36)
SCHEMBL7254413 0.79 HIF1A (0.36)
SCHEMBL13677583 0.71 HIF1A (0.34)
SCHEMBL5097862 0.71 KDM4E (0.40)
SCHEMBL7119512 0.71 KDM1A (0.39)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6627121-B1 Plastic lenses; high optical density on photoactivation; high fatigue resistance; fast decoloration in dark YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) 2003-09-30 US claimed
US-6627121-B1 Plastic lenses; high optical density on photoactivation; high fatigue resistance; fast decoloration in dark YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) 2003-09-30 US disclosed