Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 7/20 | 0.44 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.42 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.42 |
| ▸ | ITGAL | P20701 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | JAK2 | O60674 | 1/20 | 0.41 |
| ▸ | JAK1 | P23458 | 1/20 | 0.41 |
| ▸ | TYK2 | P29597 | 1/20 | 0.41 |
| ▸ | BACE1 | P56817 | 1/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CES2 | O00748 | 1/20 | 0.39 |
| ▸ | CES1 | P23141 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL642255 | 0.86 | CES2 (0.46) | GAAITGB2ICAM1ITGALKMT2A | |
| SCHEMBL102502 | 0.86 | ALDH1A1 (0.50) | PBRM1GAAALDH1A1TAAR1KMT2A | |
| SCHEMBL102501 | 0.86 | ALDH1A1 (0.50) | PBRM1GAAALDH1A1TAAR1KMT2A | |
| SCHEMBL642256 | 0.86 | CES2 (0.46) | GAAITGB2ICAM1ITGALKMT2A | |
| SCHEMBL8378366 | 0.78 | CES2 (0.40) | GAAITGB2ICAM1ITGALALDH1A1 | |
| SCHEMBL11911197 | 0.78 | ALDH1A1 (0.48) | PBRM1GAAALDH1A1JAK2JAK1 | |
| SCHEMBL29387927 | 0.78 | ALDH1A1 (0.48) | PBRM1GAAALDH1A1JAK2JAK1 | |
| SCHEMBL11893724 | 0.78 | ALDH1A1 (0.48) | PBRM1GAAALDH1A1JAK2JAK1 | |
| SCHEMBL8381824 | 0.78 | ALDH1A1 (0.43) | PBRM1GAAALDH1A1JAK1TAAR1 | |
| SCHEMBL5772875 | 0.78 | ALDH1A1 (0.48) | PBRM1GAAALDH1A1JAK2JAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030078437-A1 | Novel benzamidoxime derivatives, intermediates and process for their preparation, and their use as fungicides | EICKEN KARL (DE) | 2003-04-24 | — | — | US | disclosed |
| US-6417398-B1 | Benzamidoxim derivatives, intermediate products and methods for preparing them, and their use as fungicides | BASF AKTIENGESELLSCHAFT (DE) | 2002-07-09 | — | — | US | disclosed |
| EP-1017671-A1 | NOVEL BENZAMIDOXIM DERIVATIVES, INTERMEDIATE PRODUCTS AND METHODS FOR PREPARING THEM, AND THEIR USE AS FUNGICIDES | BASF AKTIENGESELLSCHAFT (DE) | 2000-07-12 | — | — | EP | disclosed |
| WO-1999014188-A1 | NOVEL BENZAMIDOXIM DERIVATIVES, INTERMEDIATE PRODUCTS AND METHODS FOR PREPARING THEM, AND THEIR USE AS FUNGICIDES | BASF AKTIENGESELLSCHAFT (DE) | 1999-03-25 | — | — | WO | disclosed |
| US-4845095-A | ANALGESICS, NEUROLEPTICS | A/S FERROSAN (DK) | 1989-07-04 | — | — | US | disclosed |
| EP-0285032-A1 | 4-Phenylpiperidine compounds and their preparation and use | A/S FERROSAN (DK) | 1988-10-05 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030078437-A1 | Novel benzamidoxime derivatives, intermediates and process for their preparation, and their use as fungicides | CBR1, CYP1B1, CYP2E1 | PBRM1 154/4885GAA 3271/4885ITGB2 2189/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.