SCHEMBL724223

SCHEMBL724223

Clc1ccc(OCCCOc2ccc(Cl)cc2I)c(I)c1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
S1PR4 O95977 6/20 0.46
MAPT P10636 1/20 0.42
MAOA P21397 2/20 0.42
MAOB P27338 2/20 0.42
F2 P00734 1/20 0.41
PLAU P00749 1/20 0.41
ST14 Q9Y5Y6 1/20 0.41
KDM4E B2RXH2 1/20 0.41
TP53 P04637 1/20 0.41
ALOX15 P16050 1/20 0.41
ALDH1A1 P00352 3/20 0.40
LMNA P02545 3/20 0.40
HPGD P15428 3/20 0.40
TSHR P16473 3/20 0.40
NPC1 O15118 2/20 0.40
MAPK1 P28482 2/20 0.40
RAB9A P51151 2/20 0.40
SMN1; SMN2 Q16637 2/20 0.40
CYP1A2 P05177 1/20 0.40
CYP3A4 P08684 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22135563 0.96 S1PR4 (0.46) S1PR4MAPTMAOAMAOBF2
SCHEMBL3902051 0.92 S1PR4 (0.44) S1PR4MAPTMAOAMAOBF2
SCHEMBL13652160 0.90 S1PR4 (0.43) S1PR4MAPTMAOAMAOBF2
SCHEMBL725616 0.89 S1PR4 (0.40) S1PR4MAPTSMN1; SMN2
SCHEMBL14028924 0.89 L3MBTL1 (0.49) S1PR4MAPTALDH1A1HPGDTSHR
SCHEMBL2620648 0.87 L3MBTL1 (0.45) S1PR4MAPTKDM4EALDH1A1HPGD
SCHEMBL2122615 0.84 MAPK1 (0.49) MAPTMAOAMAOBKDM4EALDH1A1
SCHEMBL814458 0.84 MAPT (0.46) S1PR4MAPTKDM4ETP53ALOX15
SCHEMBL2123126 0.83 FFAR1 (0.43) LMNATSHRSMN1; SMN2
SCHEMBL22135524 0.79 ALDH1A1 (0.44) S1PR4MAPTMAOAMAOBKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9029487-B2 Process for polymerizing a polymerizable olefin and catalyst therefor DOW GLOBAL TECHNOLOGIES LLC (US) 2015-05-12 US disclosed
US-9029487-B2 Process for polymerizing a polymerizable olefin and catalyst therefor DOW GLOBAL TECHNOLOGIES LLC (US) 2015-05-12 US disclosed
US-9029487-B2 Process for polymerizing a polymerizable olefin and catalyst therefor DOW GLOBAL TECHNOLOGIES LLC (US) 2015-05-12 US disclosed
EP-2609123-A1 PROCESS FOR POLYMERIZING A POLYMERIZABLE OLEFIN AND CATALYST THEREFOR Dow Global Technologies LLC (US) 2013-07-03 EP disclosed
US-20130144018-A1 PROCESS FOR POLYMERIZING A POLYMERIZABLE OLEFIN AND CATALYST THEREFOR DOW GLOBAL TECHNOLOGIES LLC (US) 2013-06-06 US disclosed
US-20130144018-A1 PROCESS FOR POLYMERIZING A POLYMERIZABLE OLEFIN AND CATALYST THEREFOR DOW GLOBAL TECHNOLOGIES LLC (US) 2013-06-06 US disclosed
US-20130144018-A1 PROCESS FOR POLYMERIZING A POLYMERIZABLE OLEFIN AND CATALYST THEREFOR DOW GLOBAL TECHNOLOGIES LLC (US) 2013-06-06 US disclosed
WO-2012027448-A1 PROCESS FOR POLYMERIZING A POLYMERIZABLE OLEFIN AND CATALYST THEREFOR DOW GLOBAL TECHNOLOGIES LLC (US) 2012-03-01 WO disclosed
WO-2012027448-A1 PROCESS FOR POLYMERIZING A POLYMERIZABLE OLEFIN AND CATALYST THEREFOR DOW GLOBAL TECHNOLOGIES LLC (US) 2012-03-01 WO disclosed