SCHEMBL725616

SCHEMBL725616

Fc1ccc(OCCCOc2ccc(Cl)cc2I)c(I)c1

nearest known ligand 0.40

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
S1PR4 O95977 6/20 0.40
HTR2C P28335 2/20 0.40
SLC6A4 P31645 2/20 0.40
HTR2B P41595 2/20 0.40
PTGDR2 Q9Y5Y4 1/20 0.37
ADRA1D P25100 1/20 0.37
DRD2 P14416 1/20 0.37
DRD4 P21917 1/20 0.37
DRD3 P35462 1/20 0.37
MAPT P10636 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL725628 0.89 F2 (0.41) HTR2CHTR2B
SCHEMBL724223 0.89 S1PR4 (0.46) S1PR4MAPTSMN1; SMN2
SCHEMBL22135563 0.86 S1PR4 (0.46) S1PR4MAPTSMN1; SMN2
SCHEMBL20516081 0.86 F2 (0.44) HTR2CHTR2BMAPT
SCHEMBL15065521 0.84 CYP1A2 (0.39) S1PR4HTR2CHTR2B
SCHEMBL19382957 0.83 F2 (0.37) S1PR4HTR2CHTR2B
SCHEMBL3902051 0.82 S1PR4 (0.44) S1PR4MAPTSMN1; SMN2
SCHEMBL13652160 0.81 S1PR4 (0.43) S1PR4MAPTSMN1; SMN2
SCHEMBL15847648 0.79 F2 (0.37) HTR2CHTR2B
SCHEMBL29066374 0.79 CYP1A2 (0.44) HTR2CHTR2BSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9029487-B2 Process for polymerizing a polymerizable olefin and catalyst therefor DOW GLOBAL TECHNOLOGIES LLC (US) 2015-05-12 US disclosed
EP-2609123-A1 PROCESS FOR POLYMERIZING A POLYMERIZABLE OLEFIN AND CATALYST THEREFOR Dow Global Technologies LLC (US) 2013-07-03 EP disclosed
US-20130144018-A1 PROCESS FOR POLYMERIZING A POLYMERIZABLE OLEFIN AND CATALYST THEREFOR DOW GLOBAL TECHNOLOGIES LLC (US) 2013-06-06 US disclosed
WO-2012027448-A1 PROCESS FOR POLYMERIZING A POLYMERIZABLE OLEFIN AND CATALYST THEREFOR DOW GLOBAL TECHNOLOGIES LLC (US) 2012-03-01 WO disclosed
WO-2012027448-A1 PROCESS FOR POLYMERIZING A POLYMERIZABLE OLEFIN AND CATALYST THEREFOR DOW GLOBAL TECHNOLOGIES LLC (US) 2012-03-01 WO disclosed