Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.63 |
| ▸ | CES2 | O00748 | 2/20 | 0.59 |
| ▸ | HTT | P42858 | 2/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | CA7 | P43166 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.50 |
| ▸ | KCNK3 | O14649 | 2/20 | 0.49 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27536386 | 0.93 | NPSR1 (0.56) | NPSR1CES2HTTRAB9AMAPT | |
| SCHEMBL7471082 | 0.92 | NPSR1 (0.55) | NPSR1CES2HTTRAB9AMAPT | |
| SCHEMBL12142256 | 0.85 | ACHE (0.57) | NPSR1HTTRAB9AMAPTNPC1 | |
| SCHEMBL43683 | 0.82 | NPC1 (0.65) | HTTRAB9AMAPTNPC1SMN1; SMN2 | |
| SCHEMBL40351 | 0.81 | CES2 (0.65) | NPSR1CES2HTTRAB9AMAPT | |
| SCHEMBL31355711 | 0.81 | CES2 (0.65) | NPSR1CES2HTTRAB9AMAPT | |
| SCHEMBL31406174 | 0.81 | CES2 (0.69) | NPSR1CES2MAPTLMNAP2RX1 | |
| SCHEMBL9200320 | 0.81 | CES2 (0.69) | NPSR1CES2MAPTLMNAP2RX1 | |
| SCHEMBL10406626 | 0.80 | NPSR1 (0.46) | NPSR1CES2HTTRAB9AMAPT | |
| Ethane SCHEMBL27386119 | 0.80 | CES2 (0.62) | NPSR1CES2HTTRAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101094827-B | Benzene compound having two or more substituents | DAIICHI SANKYO CO LTD | 2012-06-13 | — | — | CN | disclosed |
| CN-101094827-A | Benzene compound having two or more substituents | SANKYO CO (JP) | 2007-12-26 | — | — | CN | disclosed |
| US-20030158428-A1 | Intermediates and processes for preparing substituted chromanol derivatives | PFIZER INC. | 2003-08-21 | — | — | US | disclosed |
| WO-2002060888-A1 | PROCESSES FOR PREPARING CHROMANYLBENZOIC ACIDS | PFIZER PRODUCTS INC. (US) | 2002-08-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030158428-A1 | Intermediates and processes for preparing substituted chromanol derivatives | CYP1A1, CYP2F1, CYP7A1 | NPSR1 1082/4885CES2 351/4885HTT 4467/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.