Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNC | P24863 | 14/20 | 0.62 |
| ▸ | CDK8 | P49336 | 14/20 | 0.62 |
| ▸ | CDK19 | Q9BWU1 | 14/20 | 0.62 |
| ▸ | DRD2 | P14416 | 3/20 | 0.44 |
| ▸ | DRD4 | P21917 | 3/20 | 0.44 |
| ▸ | CDK9 | P50750 | 2/20 | 0.38 |
| ▸ | CCNA2 | P20248 | 2/20 | 0.36 |
| ▸ | CDK2 | P24941 | 2/20 | 0.36 |
| ▸ | CCNA1 | P78396 | 2/20 | 0.36 |
| ▸ | AURKA | O14965 | 1/20 | 0.36 |
| ▸ | IKBKB | O14920 | 1/20 | 0.36 |
| ▸ | MAP3K19 | Q56UN5 | 1/20 | 0.35 |
| ▸ | HIPK1 | Q86Z02 | 1/20 | 0.35 |
| ▸ | HASPIN | Q8TF76 | 1/20 | 0.35 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7249156 | 0.87 | CCNC (0.46) | CCNCCDK8CDK19DRD2DRD4 | |
| SCHEMBL7248593 | 0.80 | CCNC (0.61) | CCNCCDK8CDK19DRD2DRD4 | |
| SCHEMBL7249277 | 0.80 | CCNC (0.63) | CCNCCDK8CDK19DRD2DRD4 | |
| SCHEMBL7241539 | 0.79 | CCNC (0.72) | CCNCCDK8CDK19DRD2DRD4 | |
| SCHEMBL15105154 | 0.79 | CCNC (0.64) | CCNCCDK8CDK19DRD2DRD4 | |
| SCHEMBL7096849 | 0.79 | CCNC (0.74) | CCNCCDK8CDK19DRD2DRD4 | |
| SCHEMBL7249264 | 0.78 | CCNC (0.66) | CCNCCDK8CDK19DRD2DRD4 | |
| SCHEMBL7243137 | 0.78 | CCNC (0.61) | CCNCCDK8CDK19DRD2DRD4 | |
| SCHEMBL7246966 | 0.78 | CCNC (0.61) | CCNCCDK8CDK19DRD2DRD4 | |
| Hydrochloric Acid SCHEMBL7241413 | 0.78 | CCNC (0.73) | CCNCCDK8CDK19DRD2DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2617726-A1 | DIABETES THERAPEUTIC AGENT | Takeda Pharmaceutical Company Limited (JP) | 2013-07-24 | — | — | EP | disclosed |
| US-20130184272-A1 | DIABETES THERAPEUTIC AGENT | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2013-07-18 | — | — | US | disclosed |
| US-20030158245-A1 | Fused heterocyclic derivatives, their production and use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2003-08-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130184272-A1 | DIABETES THERAPEUTIC AGENT | FABP4, GPR119, CPT1B | CCNC 3196/4885CDK8 4502/4885CDK19 4521/4885 |
| US-20030158245-A1 | Fused heterocyclic derivatives, their production and use | TST, STS, AHR | CCNC 2012/4885CDK8 3614/4885CDK19 2184/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.