SCHEMBL724335

SCHEMBL724335

CC(C)C(=O)Oc1ccc(CO)cc1[C@H](CCN(CC[C@@H](c1ccccc1)c1cc(CO)ccc1OC(=O)C(C)C)C(C)C)c1ccccc1

nearest known ligand 0.84

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CHRM2 P08172 3/20 0.84
CHRM1 P11229 3/20 0.84
ALOX15 P16050 1/20 0.41
ADRB2 P07550 5/20 0.38
ADRA1A P35348 2/20 0.38
ADRA2A P08913 1/20 0.38
DRD2 P14416 1/20 0.38
ADRA2C P18825 1/20 0.38
DRD1 P21728 1/20 0.38
DRD3 P35462 1/20 0.38
MAPT P10636 6/20 0.37
ALDH1A1 P00352 4/20 0.37
CHRM3 P20309 5/20 0.37
CHRM5 P08912 2/20 0.37
HRH1 P35367 2/20 0.37
CX3CR1 P49238 1/20 0.37
TMEM97 Q5BJF2 1/20 0.37
FFAR4 Q5NUL3 1/20 0.37
SIGMAR1 Q99720 1/20 0.37
LMNA P02545 3/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15140860 1.00 CHRM2 (0.84) CHRM2CHRM1ALOX15ADRB2ADRA1A
Fesoterodine SCHEMBL812986 0.91 CHRM2 (1.00) CHRM2CHRM1ALOX15ADRB2ADRA1A
Fesoterodine SCHEMBL29366015 0.91 CHRM2 (1.00) CHRM2CHRM1ALOX15ADRB2ADRA1A
Fesoterodine SCHEMBL15148766 0.91 CHRM2 (1.00) CHRM2CHRM1ALOX15ADRB2ADRA1A
Fesoterodine SCHEMBL1808421 0.91 CHRM2 (1.00) CHRM2CHRM1ALOX15ADRB2ADRA1A
Fesoterodine SCHEMBL121127 0.91 CHRM2 (1.00) CHRM2CHRM1ALOX15ADRB2ADRA1A
Fesoterodine SCHEMBL3688110 0.90 CHRM2 (0.98) CHRM2CHRM1ALOX15ADRB2ADRA1A
Fesoterodine SCHEMBL2474276 0.90 CHRM2 (0.98) CHRM2CHRM1ALOX15ADRB2ADRA1A
Fesoterodine SCHEMBL2474910 0.89 CHRM2 (0.96) CHRM2CHRM1ALOX15ADRB2ADRA1A
Fesoterodine SCHEMBL2474905 0.89 CHRM2 (0.96) CHRM2CHRM1ALOX15ADRB2ADRA1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9012678-B2 Processes for the preparation of fesoterodine CADILA HEALTHCARE LIMITED (IN) 2015-04-21 US disclosed
US-9012678-B2 Processes for the preparation of fesoterodine CADILA HEALTHCARE LIMITED (IN) 2015-04-21 US disclosed
US-9012678-B2 Processes for the preparation of fesoterodine CADILA HEALTHCARE LIMITED (IN) 2015-04-21 US disclosed
US-20130197260-A1 PROCESSES FOR THE PREPARATION OF FESOTERODINE CADILA HEALTHCARE LIMITED (IN) 2013-08-01 US disclosed
US-20130197260-A1 PROCESSES FOR THE PREPARATION OF FESOTERODINE CADILA HEALTHCARE LIMITED (IN) 2013-08-01 US disclosed
US-20130197260-A1 PROCESSES FOR THE PREPARATION OF FESOTERODINE CADILA HEALTHCARE LIMITED (IN) 2013-08-01 US disclosed
WO-2012025941-A2 PROCESSES FOR THE PREPARATION OF FESOTERODINE CADILA HEALTHCARE LIMITED (IN) 2012-03-01 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130197260-A1 PROCESSES FOR THE PREPARATION OF FESOTERODINE QDPR, FES, SULT1A1 CHRM2 211/4885CHRM1 165/4885ALOX15 4798/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.