SCHEMBL724344

SCHEMBL724344

CC(C)(C#N)COC(N)=O

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.48
HSD17B10 Q99714 1/20 0.48
ALOX15 P16050 1/20 0.41
TSHR P16473 4/20 0.37
CYP3A4 P08684 1/20 0.37
NFKB1 P19838 1/20 0.37
ADRA1A P35348 1/20 0.37
RAB9A P51151 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
CHRM2 P08172 2/20 0.34
CHRM4 P08173 2/20 0.34
CHRM5 P08912 2/20 0.34
CHRM1 P11229 2/20 0.34
CHRM3 P20309 2/20 0.34
CHRNB2 P17787 2/20 0.34
CHRNA4 P43681 2/20 0.34
HTR1A P08908 1/20 0.34
CYP2C19 P33261 1/20 0.34
CHRNA7 P36544 1/20 0.34
ALDH1A1 P00352 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26688769 0.81 LMNA (0.47) LMNAHSD17B10ALOX15TSHRCYP3A4
SCHEMBL23623232 0.80 ALDH1A1 (0.39) LMNAHSD17B10TSHRRAB9ACHRM2
SCHEMBL28632377 0.79 LMNA (0.41) LMNAHSD17B10ALOX15TSHRCYP3A4
SCHEMBL28340914 0.78 ALDH1A1 (0.32) TSHRALDH1A1
SCHEMBL9911404 0.78 LMNA (0.48) LMNAHSD17B10ALOX15TSHRCYP3A4
SCHEMBL10012056 0.78 ADRA2A (0.35) TSHRADRA1AALDH1A1
SCHEMBL8357550 0.77 ALDH1A1 (0.31) TSHRALDH1A1
SCHEMBL20759694 0.77 ALDH1A1 (0.35) TSHRALDH1A1
SCHEMBL10010089 0.75 TSHR (0.38) LMNATSHRALDH1A1
SCHEMBL1171251 0.75 ALDH1A1 (0.52) HSD17B10TSHRCYP3A4ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 301 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118355117-A Oligonucleotide compositions and methods thereof 波涛生命科学有限公司 2024-07-16 CN disclosed
CN-111936487-B Compounds for the treatment of kinase dependent disorders 埃克塞里艾克西斯公司 2024-07-09 CN disclosed
CN-111936136-B Novel imidazopyrimidine compounds and uses thereof 儿童医学中心公司 2024-07-05 CN disclosed
CN-112312909-B Compounds for the treatment of kinase dependent disorders 埃克塞里艾克西斯公司 2024-07-02 CN disclosed
CN-113710660-B DOT1L degradation agent and application thereof 达纳-法伯癌症研究公司 2024-07-02 CN disclosed
WO-2023168066-A9 OXIME-BASED HOT MELT ADHESIVES FOR REWORK, REPAIR AND RECYCLE CONAGEN INC. (US) 2024-06-20 WO disclosed
CN-118159271-A Treatment of JAK inhibition responsive conditions with prodrugs of JAK inhibitors 太阳医药工业公司 2024-06-07 CN disclosed
CN-118139977-A Double-stranded oligonucleotide compositions and methods relating thereto 波涛生命科学有限公司 2024-06-04 CN disclosed
CN-118139629-A Compositions and methods for editing MECP2 transcripts 波涛生命科学有限公司 2024-06-04 CN disclosed
CN-118076584-A Esters of retinoids and bakuchiol and formulations thereof 康纳根有限公司 2024-05-24 CN disclosed
WO-2011073970-A1 A GASTROINTESTINAL IMPLANT DEVICE VYSERA BIOMEDICAL LIMITED (IE) 2011-06-23 WO disclosed
WO-2011073967-A1 A BIOMATERIAL VYSERA BIOMEDICAL LIMITED (IE) 2011-06-23 WO disclosed
WO-2011059821-A2 CYCLOHEXANE-1,3-DIONES FOR USE IN THE TREATMENT OF AMYOTROPHIC LATERAL SCLEROSIS CAMBRIA PHARMACEUTICALS, INC. (US) 2011-05-19 WO disclosed
EP-2296581-A1 A BIOMATERIAL Vysera Biomedical Limited (IE) 2011-03-23 EP disclosed
CN-101932592-A Antineoplastic compound PHARMA MAR SA 2010-12-29 CN disclosed
WO-2010027334-A1 NOVEL TRICYCLIC CHIRAL COMPOUNDS AND THEIR USE IN ASYMMETRIC CATALYSIS NANYANG TECHNOLOGICAL UNIVERSITY (SG) 2010-03-11 WO disclosed
WO-2009153769-A1 A BIOMATERIAL VYSERA BIOMEDICAL LIMITED (IE) 2009-12-23 WO disclosed
WO-2009132032-A2 SONIC HEDGEHOG MODULATORS PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2009-10-29 WO disclosed
WO-2009042270-A9 RECA INHIBITORS AND THEIR USES AS MICROBIAL INHIBITORS OR POTENTIATORS OF ANTIBIOTIC ACTIVITY UNIV BOSTON (US) 2009-06-18 WO disclosed
WO-2009042270-A2 RECA INHIBITORS AND THEIR USES AS MICROBIAL INHIBITORS OR POTENTIATORS OF ANTIBIOTIC ACTIVITY TRUSTEES OF BOSTON UNIVERSITY (US) 2009-04-02 WO disclosed