Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 15/20 | 0.35 |
| ▸ | MAPK13 | O15264 | 10/20 | 0.35 |
| ▸ | MAPK12 | P53778 | 10/20 | 0.35 |
| ▸ | MAPK11 | Q15759 | 10/20 | 0.35 |
| ▸ | CSNK1D | P48730 | 4/20 | 0.35 |
| ▸ | GCGR | P47871 | 2/20 | 0.35 |
| ▸ | RIPK3 | Q9Y572 | 2/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Morpholine SCHEMBL7387653 | 0.85 | MAPK14 (0.39) | MAPK14MAPK13MAPK12MAPK11CSNK1D | |
| Morpholine SCHEMBL7382870 | 0.84 | ALOX5 (0.40) | MAPK14MAPK13MAPK12MAPK11CSNK1D | |
| SCHEMBL7232352 | 0.83 | MAPK14 (0.44) | MAPK14MAPK13MAPK12MAPK11GCGR | |
| SCHEMBL8490495 | 0.81 | MAPK14 (0.42) | MAPK14MAPK13MAPK12MAPK11CSNK1D | |
| Morpholine SCHEMBL4553844 | 0.72 | MAPK14 (0.49) | MAPK14MAPK13MAPK12MAPK11CSNK1D | |
| SCHEMBL5082085 | 0.68 | MAPK14 (0.45) | MAPK14MAPK13MAPK12MAPK11GCGR | |
| Morpholine SCHEMBL7990935 | 0.68 | MAPK14 (0.37) | MAPK14MAPK13MAPK12MAPK11CSNK1D | |
| Morpholine SCHEMBL4553714 | 0.67 | MAPK14 (0.49) | MAPK14MAPK13MAPK12MAPK11CSNK1D | |
| SCHEMBL4566366 | 0.67 | ADORA2A (0.46) | MAPK14MAPK13MAPK12MAPK11ALOX5 | |
| SCHEMBL8524296 | 0.66 | MAPK14 (0.46) | MAPK14MAPK13MAPK12MAPK11CSNK1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030064997-A1 | Novel compounds | SMITHKLINE BEECHAM CORPORATION | 2003-04-03 | — | — | US | disclosed |
| WO-1995003297-A1 | IMIDAZOLES FOR TREATING CYTOKINE MEDIATED DISEASE | SMITHKLINE BEECHAM CORPORATION (US) | 1995-02-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030064997-A1 | Novel compounds | BRD4, BRDT, HDAC6 | MAPK14 3769/4885MAPK13 2219/4885MAPK12 3250/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.