SCHEMBL724442

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL12788371	0.79	NPC1 (0.46)	SMN1; SMN2KDM4EALDH1A1HPGDHDAC1
	SCHEMBL724402	0.76	EGFR (0.51)	TSHRSMN1; SMN2CNR2KDM4EALDH1A1
	SCHEMBL28276198	0.74	CNR2 (0.62)	TSHRSMN1; SMN2CNR2MDM4TUBB4A
	SCHEMBL724552	0.73	NPC1 (0.64)	SMN1; SMN2ALDH1A1HDAC1HDAC6TUBB4A
	SCHEMBL12790160	0.73	ALDH1A1 (0.46)	SMN1; SMN2KDM4EALDH1A1HPGDHDAC1
	SCHEMBL12113567	0.72	CNR2 (0.54)	TSHRSMN1; SMN2FYNCNR2KDM4E
	SCHEMBL6955962	0.72	TUBB4A (0.53)	TSHRSMN1; SMN2FYNTUBB4ATUBB
	SCHEMBL7039744	0.72	ALDH1A1 (0.44)	SMN1; SMN2KDM4EALDH1A1HPGDHDAC1
	SCHEMBL724985	0.72	MEN1 (0.45)	TSHRSMN1; SMN2CNR2KDM4EALDH1A1
	SCHEMBL771479	0.71	CNR2 (0.46)	TSHRSMN1; SMN2CNR2KDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.