Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H3 | Q13133 | 2/20 | 0.40 |
| ▸ | CTSV | O60911 | 1/20 | 0.38 |
| ▸ | CTSL | P07711 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 2/20 | 0.36 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.35 |
| ▸ | BCHE | P06276 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | PER2 | O15055 | 2/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | CRY1 | Q16526 | 1/20 | 0.35 |
| ▸ | CRY2 | Q49AN0 | 1/20 | 0.35 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.35 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.34 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7526000 | 1.00 | NR1H3 (0.40) | NR1H3CTSVCTSLMAOBHCRTR2 | |
| SCHEMBL7248052 | 1.00 | NR1H3 (0.40) | NR1H3CTSVCTSLMAOBHCRTR2 | |
| SCHEMBL5194303 | 0.90 | NR1H3 (0.38) | NR1H3MAOBHCRTR2ACHEMEN1 | |
| SCHEMBL5193993 | 0.89 | NR1H3 (0.37) | NR1H3MAOBHCRTR2ACHEMEN1 | |
| SCHEMBL7250840 | 0.87 | ATM (0.40) | NR1H3CTSVCTSLMAOBHCRTR2 | |
| SCHEMBL1120784 | 0.87 | NPSR1 (0.39) | NR1H3MAOBACHEMAOAALK | |
| Hydrochloric Acid SCHEMBL7616039 | 0.85 | ADRB3 (0.48) | ADRB3ADRA1A | |
| SCHEMBL6746794 | 0.84 | NR1H3 (0.41) | NR1H3CTSVCTSLMAOBHCRTR2 | |
| SCHEMBL6744765 | 0.84 | NR1H3 (0.41) | NR1H3CTSVCTSLMAOBHCRTR2 | |
| SCHEMBL7252170 | 0.83 | HCRTR2 (0.41) | CTSVCTSLMAOBHCRTR2BCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6599892-B2 | Beta-lactamase inhitiors | RESEARCH CORPORATION TECHNOLOGIES, INC. | 2003-07-29 | — | — | US | disclosed |
| US-20030045727-A1 | Process for preparing optically active secondary alcohols having nitrogenous or oxygenic functional groups | ASAHI KASEI KABUSHIKI KAISHA (JP) | 2003-03-06 | — | — | US | disclosed |
| EP-1254885-A1 | PROCESS FOR PREPARING OPTICALLY ACTIVE SECONDARY ALCOHOLS HAVING NITROGENOUS OR OXYGENIC FUNCTIONAL GROUPS | Asahi Kasei Kabushiki Kaisha (JP) | 2002-11-06 | — | — | EP | disclosed |
| US-20020025954-A1 | 7-alkylidene cephalosporanic acid derivatives and methods of using the same | RESEARCH CORPORATION TECHNOLOGIES, INC. | 2002-02-28 | — | — | US | disclosed |
| US-6303592-B1 | AS INHIBITORS OF .BETA.-LACTAMASE ENZYMES | RESEARCH CORPORATION TECHNOLOGIES, INC. | 2001-10-16 | — | — | US | disclosed |
| WO-1996017849-A1 | 7-ALKYLIDENE CEPHALOSPORANIC ACID DERIVATIVES AND METHODS OF USING THE SAME | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 1996-06-13 | — | — | WO | disclosed |
| WO-1996017848-A1 | 7-VINYLIDENE CEPHALOSPORINS AND METHODS OF USING THE SAME | SOUTHERN METHODIST UNIVERSITY (US) | 1996-06-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030045727-A1 | Process for preparing optically active secondary alcohols having nitrogenous or oxygenic functional groups | ADH1A, ADH5, ADH1C | NR1H3 53/4885CTSV 4705/4885CTSL 4734/4885 |
| US-20020025954-A1 | 7-alkylidene cephalosporanic acid derivatives and methods of using the same | STS, PEPD, IDUA | NR1H3 3232/4885CTSV 728/4885CTSL 343/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.