SCHEMBL724513

SCHEMBL724513

Nc1ncc(I)cn1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4859450 0.72 MAP4K4 (0.56)
SCHEMBL17551961 0.72
SCHEMBL2495212 0.72
SCHEMBL18151 0.67
SCHEMBL163787 0.67
SCHEMBL1151828 0.67
SCHEMBL1763130 0.67
SCHEMBL15047762 0.67
SCHEMBL40335 0.67
SCHEMBL11834 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 407 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107930588-A Lithium base magnetism montmorillonite for the pollution of Adsorption caesium and preparation method thereof 北京源清益壤环保科技有限公司 2018-04-20 CN claimed
WO-2013090873-A1 A COMPOSITION AND METHOD FOR REDUCING CYANURIC ACID IN RECREATIONAL WATER HAVILAND PRODUCTS COMPANY (US) 2013-06-20 WO claimed
US-12630529-B2 GCN2 modulator compounds Alesta Therapeutics BV (NL) 2026-05-19 US disclosed
US-20260047580-A1 HETEROCYCLIC COMPOUND AND HARMFUL ARTHROPOD PEST CONTROL COMPOSITION CONTAINING SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2026-02-19 US disclosed
EP-4658667-A1 CYCLIC PEPTIDES FOR INHIBITING TNF RECEPTOR 1 ACTIVITY Merck Sharp & Dohme LLC (US) 2025-12-10 EP disclosed
US-12478067-B2 Heterocyclic compound and harmful arthropod pest control composition containing same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2025-11-25 US disclosed
WO-2025016138-A1 HETEROCYCLIC COMPOUNDS AND USES THEREOF SUZHOU EOC MEDICAL RESEARCH CO., LTD. (CN) 2025-01-23 WO disclosed
US-20240391900-A1 RIP1 KINASE INHIBITOR AND USE THEREOF SIRONAX (BEIJING) CO., LTD. (CN) 2024-11-28 US disclosed
CN-118908899-A FGFR4 inhibitor and preparation and application thereof 重庆医科大学 2024-11-08 CN disclosed
CN-115947693-B FGFR4 inhibitor and preparation and application thereof 重庆医科大学 2024-11-05 CN disclosed
EP-3498693-B1 HETEROCYCLIC COMPOUND TAKEDA PHARMACEUTICALS CO (JP) 2024-10-30 EP disclosed
US-20040152704-A1 Bicyclic-substituted amines as histamine-3 receptor ligands ABBVIE INC. 2004-08-05 US disclosed
WO-2004043458-A1 BICYCLIC-SUBSTITUTED AMINES AS HISTAMINE-3 RECEPTOR LIGANDS ABBOTT LABORATORIES (US) 2004-05-27 WO disclosed
EP-1071645-A4 PHOSPHODIESTERASE ISOENZYME DENOMINATED 4 (PDE 4) INHIBITING COMPOUNDS SMITHKLINE BEECHAM CORP (US) 2003-04-02 EP disclosed
US-6518306-B1 PDE4 inhibitors particularly in regards to treating allergic and inflammatory diseases SMITHKLINE BEECHAM CORPORATION 2003-02-11 US disclosed
EP-1071645-A1 PHOSPHODIESTERASE ISOENZYME DENOMINATED 4 (PDE 4) INHIBITING COMPOUNDS SMITHKLINE BEECHAM CORPORATION (US) 2001-01-31 EP disclosed
US-6172118-B1 Compounds SMITHKLINE BEECHAM CORPORATION 2001-01-09 US disclosed
WO-1999052847-A1 PHOSPHODIESTERASE ISOENZYME DENOMINATED 4 (PDE 4) INHIBITING COMPOUNDS SMITHKLINE BEECHAM CORPORATION (US) 1999-10-21 WO disclosed
US-4605655-A NEUROLEPTIC AGENTS; NO MOVEMENT DISORDER SIDE EFFECTS BRISTOL-MYERS COMPANY (US) 1986-08-12 US disclosed
US-4248618-A Derivatives of (pyrimidyloxy)phenoxy-alkanecarboxylic acid and herbicidal compositions thereof ICI AUSTRALIA LIMITED (AU) 1981-02-03 US disclosed