SCHEMBL7245446

SCHEMBL7245446

CCCCCCCCCCCCCCCCOc1ccc(C(=NOS(=O)(=O)CCC)C(F)(F)F)cc1

nearest known ligand 0.49

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
TP53 P04637 2/20 0.49
TSHR P16473 1/20 0.49
PLA2G4B P0C869 6/20 0.48
RARB P10826 3/20 0.46
NPC1 O15118 1/20 0.46
LMNA P02545 1/20 0.46
GAA P10253 1/20 0.46
MAPT P10636 1/20 0.46
ALOX15 P16050 1/20 0.46
RAB9A P51151 1/20 0.46
HSD17B10 Q99714 1/20 0.46
THRA P10827 2/20 0.44
THRB P10828 2/20 0.44
PLA2G4A P47712 1/20 0.44
NR5A1 Q13285 1/20 0.43
SLC2A1 P11166 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7245963 1.00 TP53 (0.49) TP53TSHRPLA2G4BRARBNPC1
SCHEMBL14947458 0.94 PLA2G4B (0.42) TP53TSHRPLA2G4BRARBNPC1
SCHEMBL546645 0.94 PLA2G4B (0.42) TP53TSHRPLA2G4BRARBNPC1
SCHEMBL546644 0.94 PLA2G4B (0.42) TP53TSHRPLA2G4BRARBNPC1
SCHEMBL178355 0.94 PLA2G4B (0.42) TP53TSHRPLA2G4BRARBNPC1
SCHEMBL3215754 0.93 PLA2G4B (0.42) TP53TSHRPLA2G4BRARBNPC1
SCHEMBL2610387 0.93 PLA2G4B (0.48) TP53TSHRPLA2G4BRARBNPC1
SCHEMBL14556415 0.93 L3MBTL1 (0.45) TP53TSHRPLA2G4BLMNAGAA
SCHEMBL546992 0.90 PLA2G4B (0.44) TP53TSHRPLA2G4BRARBNPC1
SCHEMBL2610386 0.90 PLA2G4B (0.44) TP53TSHRPLA2G4BRARBNPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6512020-B1 Photosensitive acid-donors in chemically amplified resist formulations. activated by irradiation with actinic electromagnetic radiation and electron beams. CIBA SPECIALTY CHEMICALS CORPORATION 2003-01-28 US disclosed
US-6261738-B1 LATENT CURING CATALYSTS FOR PHOTORESISTS SUCH AS 2,2,2-TRIFLUORO-1-PHENYL-ETHANONE OXIME-O-METHYL SULFONATE CIBA SPECIALTY CHEMICALS CORPORATION 2001-07-17 US disclosed