Sugi Predict

Sugi Predict / Compounds / SCHEMBL724626

SCHEMBL724626

SCHEMBL724626

Cc1c(N)ccc2[nH]ccc12

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ AHR P35869 1/20 0.38
▸ CYP3A4 P08684 1/20 0.37
▸ TSHR P16473 1/20 0.37
▸ PIK3CA P42336 1/20 0.37
▸ PARP1 P09874 2/20 0.36
▸ P2RX7 Q99572 2/20 0.35
▸ RPS6KA3 P51812 1/20 0.35
▸ RECQL P46063 1/20 0.34
▸ TDP1 Q9NUW8 1/20 0.34
▸ KDM4E B2RXH2 1/20 0.34
▸ ALDH1A1 P00352 1/20 0.34
▸ GLA P06280 1/20 0.34
▸ GAA P10253 1/20 0.34
▸ HPGD P15428 1/20 0.34
▸ HSD17B10 Q99714 1/20 0.34
▸ DHFR P00374 1/20 0.34
▸ MAPK1 P28482 1/20 0.33
▸ POLB P06746 1/20 0.33
▸ HTR1D P28221 3/20 0.33
▸ HTR1B P28222 3/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8404367 0.77 AHR (0.40) AHRTSHRPARP1P2RX7DHFR
SCHEMBL2979916 0.75 RHEB (0.41) AHRP2RX7KDM4EALDH1A1MAPK1
SCHEMBL31431597 0.74 AHR (0.38) AHRPARP1RECQLTDP1MAPK1
SCHEMBL18529441 0.74 AHR (0.47) AHRPARP1RECQLTDP1MAPK1
SCHEMBL31432146 0.74 AHR (0.47) AHRPARP1RECQLTDP1MAPK1
SCHEMBL28906650 0.74 RHEB (0.40) AHRCYP3A4PARP1P2RX7RECQL
SCHEMBL2985458 0.74 AHR (0.38) AHRPARP1RECQLTDP1MAPK1
SCHEMBL8995172 0.74 AHR (0.52) AHRPARP1P2RX7HTR1DHTR1B
SCHEMBL31005469 0.74 P2RX7 (0.38) AHRCYP3A4PARP1P2RX7KDM4E
SCHEMBL2976758 0.74 AHR (0.38) AHRPARP1P2RX7HTR1DHTR1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 72 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110643032-B Eight-arm polyethylene glycol, preparation method, functionalized derivative and modified biologically-relevant substance 厦门赛诺邦格生物科技股份有限公司 2022-01-28 — — CN claimed
CN-110643032-A Eight-arm polyethylene glycol, preparation method, functionalized derivative and modified biologically-relevant substance 厦门赛诺邦格生物科技股份有限公司 2020-01-03 — — CN claimed
CN-106967213-B Eight-arm polyethylene glycol, preparation method, functionalized derivative and modified biologically-relevant substance 厦门赛诺邦格生物科技股份有限公司 2019-11-05 — — CN claimed
CN-106967213-A Eight-arm polyethylene glycol, preparation method, functionalized derivative and modified biologically-relevant substance 厦门赛诺邦格生物科技股份有限公司 2017-07-21 — — CN claimed
US-9670305-B2 Polyurethane dispersant and the method for its preparation Wang, Zhijun (CN) 2017-06-06 — — US claimed
EP-2839873-B1 POLYURETHANE DISPERSANT AND PREPARATION METHOD THEREOF WANG ZHIJUN (CN) 2017-01-04 — — EP claimed
US-20150065676-A1 POLYURETHANE DISPERSANT AND THE METHOD FOR ITS PREPARATION AFCONA CHEMICALS (HAIMEN) CO., LTD. (CN) 2015-03-05 — — US claimed
EP-2839873-A1 POLYURETHANE DISPERSANT AND PREPARATION METHOD THEREOF Wang, Zhijun (CN) 2015-02-25 — — EP claimed
CN-102658057-B Novel polyurethane dispersant and preparation method thereof WANG ZHIJUN 2014-09-10 — — CN claimed
CN-102658057-A Novel polyurethane dispersant and preparation method thereof ZHIJUN WANG 2012-09-12 — — CN claimed
WO-2025245484-A1 FOXN1 ACTIVATORS THYMOFOX INC. (US) 2025-11-27 — — WO disclosed
US-11324827-B2 Multifunctionalized polyethylene glycol derivative and preparation method therefor XIAMEN SINOPEG BIOTECH CO., LTD. (CN) 2022-05-10 — — US disclosed
CN-110643032-B Eight-arm polyethylene glycol, preparation method, functionalized derivative and modified biologically-relevant substance 厦门赛诺邦格生物科技股份有限公司 2022-01-28 — — CN disclosed
EP-3763710-A1 THERAPEUTIC COMPOUNDS AND USES THEREOF Kala Pharmaceuticals, Inc. (US) 2021-01-13 — — EP disclosed
WO-2020142748-A1 METHODS AND MATERIALS FOR INCREASING TRANSCRIPTION FACTOR EB POLYPEPTIDE LEVELS UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) 2020-07-09 — — WO disclosed
US-6040451-A USED AS ANALGESIC, SEDATIVE AND ANAESTHETIC AGENTS SYNAPTIC PHARMACEUTICAL CORPORATION (US) 2000-03-21 — — US disclosed
US-5948804-A ANAESTHETIC PREMEDICATION SYNAPTIC PHARMACEUTICAL CORPORATION (US) 1999-09-07 — — US disclosed
EP-0900080-A1 NOVEL INDOLE AND BENZOTHIAZOLE DERIVATIVES SYNAPTIC PHARMACEUTICAL CORPORATION (US) 1999-03-10 — — EP disclosed
US-5677321-A ANESTHETIC PREMEDICATION SYNAPTIC PHARMACEUTICAL CORPORATION (US) 1997-10-14 — — US disclosed
WO-1997031636-A1 NOVEL INDOLE AND BENZOTHIAZOLE DERIVATIVES SYNAPTIC PHARMACEUTICAL CORPORATION (US) 1997-09-04 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11324827-B2 Multifunctionalized polyethylene glycol derivative and preparation method therefor HDGF, F11, F12 AHR 4517/4885CYP3A4 2743/4885TSHR 1973/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.