SCHEMBL724669

SCHEMBL724669

COC1=C(OC)C2CCC1C2

nearest known ligand 0.36

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
ADRA1A P35348 2/20 0.36
SLC6A3 Q01959 3/20 0.32
HIF1A Q16665 1/20 0.31
HTR2C P28335 1/20 0.30
KDM1A O60341 1/20 0.30
MAOA P21397 1/20 0.30
MAOB P27338 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9589558 0.71 ADRA1A (0.67) ADRA1AHIF1AHTR2C
SCHEMBL13602100 0.69 ADRA1A (0.37) ADRA1A
SCHEMBL9719087 0.66 PTAFR (0.58) HIF1A
SCHEMBL30414626 0.66
SCHEMBL9191167 0.64
SCHEMBL17373003 0.63
SCHEMBL12297790 0.63 HTR2C (0.50) ADRA1AHTR2C
SCHEMBL1012684 0.62 HSD17B10 (0.31) KDM1AMAOAMAOB
SCHEMBL2953403 0.62 ADRA1A (0.32) ADRA1A
SCHEMBL6559739 0.62

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 238 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2970522-B1 IN-MOLD COATING OF ROMP POLYMERS MATERIA INC (US) 2025-05-21 EP claimed
CN-119101214-A Cycloolefin metathesis composition and polymerization method thereof 道生天合材料科技(上海)股份有限公司 2024-12-10 CN claimed
US-12043573-B2 Adhesion promoters and gel-modifiers for olefin metathesis compositions MATERIA, INC. (US) 2024-07-23 US claimed
US-20240043608-A1 METHOD AND COMPOSITION FOR IMPROVING ADHESION OF METATHESIS COMPOSITIONS TO SUBSTRATES MATERIA, INC. (US) 2024-02-08 US claimed
EP-3256505-B1 CYCLIC OLEFIN RESIN COMPOSITIONS COMPRISING FUNCTIONAL ELASTOMERS MATERIA INC (US) 2023-11-29 EP claimed
US-20220089481-A1 ADHESION PROMOTERS AND GEL-MODIFIERS FOR OLEFIN METATHESIS COMPOSITIONS MATERIA, INC. (US) 2022-03-24 US claimed
US-20210403654-A1 ADHESION PROMOTER COMPOSITIONS FOR CYCLIC OLEFIN RESIN COMPOSITIONS MATERIA, INC. (US) 2021-12-30 US claimed
US-10907018-B2 Adhesion promoter compositions for cyclic olefin resin compositions MATERIA, INC. (US) 2021-02-02 US claimed
US-10633484-B2 Method and composition for improving adhesion of metathesis compositions to substrates MATERIA, INC. (US) 2020-04-28 US claimed
US-20200115277-A1 ADHESION PROMOTERS AND GEL-MODIFIERS FOR OLEFIN METATHESIS COMPOSITIONS MATERIA, INC. (US) 2020-04-16 US claimed
US-20180237581-A1 METHOD AND COMPOSITION FOR IMPROVING ADHESION OF METATHESIS COMPOSITIONS TO SUBSTRATES MATERIA, INC. (US) 2018-08-23 US claimed
US-9803046-B2 In-mold coating of ROMP polymers MATERIA, INC. (US) 2017-10-31 US claimed
US-12630738-B2 In-mold coating crosslinkers, compositions, systems, processes and articles RED SPOT PAINT & VARNISH CO., INC. (US) 2026-05-19 US disclosed
WO-2026090602-A1 PIGMENTED RESIN AND CATALYST COMPOSITIONS MATERIA, INC. (US) 2026-04-30 WO disclosed
EP-3110862-B1 ADHESION PROMOTER COMPOSITIONS FOR CYCLIC OLEFIN RESIN COMPOSITIONS ExxonMobil Product Solutions Company (US) 2026-04-01 EP disclosed
EP-4683900-A2 ROMP AND THERMAL INSULATION COMPOSITIONS AND MATERIALS AND USE THEREOF Materia, Inc. (US) 2026-01-28 EP disclosed
CN-1512974-A Selective ring-opening cross-metathesis of cycloulefins 加利福尼亚技术学院 2004-07-14 CN disclosed
EP-1379485-A1 SELECTIVE RING-OPENING CROSS-METATHESIS OF CYCLOOLEFINS California Institute of Technology (US) 2004-01-14 EP disclosed
US-20020198426-A1 Selective ring-opening cross-metathesis of cycloolefins CYMETECH, LLC 2002-12-26 US disclosed
WO-2002079127-A1 SELECTIVE RING-OPENING CROSS-METATHESIS OF CYCLOOLEFINS CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 2002-10-10 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020198426-A1 Selective ring-opening cross-metathesis of cycloolefins KMO, COASY, OXER1 ADRA1A 2057/4885SLC6A3 4481/4885HIF1A 4264/4885
US-12630738-B2 In-mold coating crosslinkers, compositions, systems, processes and articles UROD, DUOX1, PDCD2L ADRA1A 3171/4885SLC6A3 4378/4885HIF1A 3355/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.