Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.42 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.42 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | KCNA1 | Q09470 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | TOP1 | P11387 | 1/20 | 0.40 |
| ▸ | RAD52 | P43351 | 1/20 | 0.37 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3424113 | 0.91 | ALDH1A1 (0.42) | CYP3A4CYP17A1CYP19A1CYP11B1CYP11B2 | |
| SCHEMBL26095376 | 0.89 | ALDH1A1 (0.40) | CYP3A4CYP17A1CYP19A1CYP11B1CYP11B2 | |
| SCHEMBL26096051 | 0.89 | ALDH1A1 (0.40) | CYP3A4CYP17A1CYP19A1CYP11B1CYP11B2 | |
| SCHEMBL245938 | 0.89 | MAPT (0.43) | CYP3A4ALDH1A1LMNAMAPTCYP2D6 | |
| SCHEMBL28121369 | 0.84 | CYP3A4 (0.50) | CYP3A4ALDH1A1LMNAMAPTMEN1 | |
| SCHEMBL3999316 | 0.84 | CYP3A4 (0.50) | CYP3A4ALDH1A1LMNAMAPTMEN1 | |
| SCHEMBL28121300 | 0.84 | CYP3A4 (0.50) | CYP3A4ALDH1A1LMNAMAPTMEN1 | |
| SCHEMBL7240131 | 0.82 | AXL (0.42) | CYP3A4ALDH1A1LMNAMAPTMEN1 | |
| SCHEMBL9582303 | 0.82 | RPS6KA3 (0.43) | CYP3A4CYP17A1CYP19A1CYP11B1CYP11B2 | |
| SCHEMBL6493307 | 0.82 | NPC1 (0.40) | ALDH1A1LMNAMAPTMEN1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030203888-A1 | Chromophores | WELLCOME TRUST LIMITED, THE (GB) | 2003-10-30 | — | — | US | disclosed |
| US-20030105130-A1 | Thiaporphyrin, selenaporphyrin, and carotenoid porphyrin compounds as c-myc and telomerase inhibitors | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2003-06-05 | — | — | US | disclosed |
| EP-1294726-A2 | IMPROVEMENTS IN AND RELATING TO CHROMOPHORES | Catalyst Biomedica Ltd (GB) | 2003-03-26 | — | — | EP | disclosed |
| WO-2002000662-A1 | IMPROVEMENTS IN AND RELATING TO CHROMOPHORES | CATALYST BIOMEDICA LIMITED (GB) | 2002-01-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030203888-A1 | Chromophores | HCCS, PPOX, HMBS | CYP3A4 1750/4885CYP17A1 3519/4885CYP19A1 2552/4885 |
| US-20030105130-A1 | Thiaporphyrin, selenaporphyrin, and carotenoid porphyrin compounds as c-myc and telomerase inhibitors | MYCBP, MYC, TERF2IP | CYP3A4 2410/4885CYP17A1 4120/4885CYP19A1 4069/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.