Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 4/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 4/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6713344 | 0.77 | CYP2C19 (0.42) | CYP1A2CYP2C19SMN1; SMN2CYP2C9MAPT | |
| SCHEMBL842220 | 0.77 | MAPT (0.37) | CYP1A2CYP2C19CYP2C9MAPTTLR7 | |
| SCHEMBL5117067 | 0.76 | MAPT (0.39) | CYP1A2CYP2C19CYP2C9MAPTTLR7 | |
| SCHEMBL6218333 | 0.72 | ESR1 (0.45) | SMN1; SMN2TLR7HRH4MEN1KMT2A | |
| SCHEMBL12763789 | 0.71 | TLR7 (0.66) | CYP1A2CYP2C19SMN1; SMN2TLR7MEN1 | |
| SCHEMBL6218252 | 0.68 | HTT (0.38) | CYP1A2CYP2C19SMN1; SMN2ALDH1A1HRH4 | |
| SCHEMBL16828172 | 0.67 | CDK1 (0.47) | SMN1; SMN2ALDH1A1HRH4MEN1KMT2A | |
| SCHEMBL16828235 | 0.65 | ADORA2A (0.55) | SMN1; SMN2MAPTALDH1A1KMT2APOLB | |
| SCHEMBL28958821 | 0.64 | TLR7 (0.64) | TLR7NCF1 | |
| SCHEMBL16482390 | 0.63 | NLRP3 (0.46) | SMN1; SMN2TLR7HPGDMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030232852-A1 | Process for imidazo[4,5-c]pyridin-4-amines | 3M INNOVATIVE PROPERTIES COMPANY | 2003-12-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030232852-A1 | Process for imidazo[4,5-c]pyridin-4-amines | CPNE4, HTR4, IL4 | CYP1A2 319/4885CYP2C19 94/4885SMN1; SMN2 1514/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.