Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6628132 | 0.88 | HTR1A (0.52) | HTR1ASLC6A4 | |
| SCHEMBL4335129 | 0.82 | NR3C1 (0.37) | HTR1ASLC6A4 | |
| SCHEMBL6629005 | 0.79 | HTR1A (0.60) | HTR1ASLC6A4 | |
| SCHEMBL6796362 | 0.76 | HTR1A (0.49) | HTR1ASLC6A4 | |
| SCHEMBL7034985 | 0.76 | HTR1A (0.53) | HTR1ASLC6A4 | |
| SCHEMBL6631639 | 0.76 | KDM4E (0.37) | — | |
| SCHEMBL6767230 | 0.75 | HTR1A (0.50) | HTR1ASLC6A4 | |
| SCHEMBL6906137 | 0.73 | HTR1A (0.39) | HTR1A | |
| SCHEMBL7215975 | 0.73 | HTR1A (0.60) | HTR1ASLC6A4 | |
| SCHEMBL6628211 | 0.72 | HTR1A (0.65) | HTR1ASLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6599915-B2 | 5HT1A antagonist limit the negative feedback of autoceptors seen with serotonic reuptake inhibitors | WYETH | 2003-07-29 | — | — | US | disclosed |