Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XDH | P47989 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.43 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.41 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.38 |
| ▸ | FEN1 | P39748 | 1/20 | 0.38 |
| ▸ | F2RL3 | Q96RI0 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8171565 | 0.82 | POLB (0.46) | POLBHTTMAPK1CYP11B1CYP11B2 | |
| SCHEMBL7165398 | 0.82 | POLB (0.63) | POLBHTTMAPK1TP53KMT2A | |
| SCHEMBL8126668 | 0.74 | MAPK1 (0.54) | POLBHTTMAPK1CYP11B1CYP11B2 | |
| SCHEMBL7252343 | 0.73 | MAPK1 (0.40) | POLBHTTMAPK1TP53KMT2A | |
| SCHEMBL7250957 | 0.72 | CYP11B1 (0.52) | XDHCYP11B1ADRA2CCYP11B2SMN1; SMN2 | |
| SCHEMBL7252340 | 0.71 | KDM4E (0.49) | POLBMAPK1ADRA2CSMN1; SMN2MAPT | |
| SCHEMBL10639259 | 0.70 | POLB (0.49) | POLBHTTMAPK1TDP1KMT2A | |
| SCHEMBL7195630 | 0.70 | CYP11B1 (0.56) | POLBHTTMAPK1CYP11B1CYP11B2 | |
| SCHEMBL10546416 | 0.69 | CCR2 (0.40) | POLBHTTMAPK1CYP11B1CYP11B2 | |
| SCHEMBL93041 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6630593-B1 | A process for preparing a 1-substituted 5-hydroxymethylimidazole of the formula: wherein R represents alkyl, hydroxyalkyl, allyl, or substituted or unsubstituted arylmethyl or diarylmethyl, comprising the step of reacting a | LG CHEM INVESTMENT LTD. (KR) | 2003-10-07 | — | — | US | disclosed |