Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACMSD | Q8TDX5 | 2/20 | 0.50 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.46 |
| ▸ | CDK8 | P49336 | 1/20 | 0.43 |
| ▸ | PRKCI | P41743 | 1/20 | 0.41 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.41 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.41 |
| ▸ | BCL2 | P10415 | 1/20 | 0.41 |
| ▸ | BACE1 | P56817 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | MMP3 | P08254 | 1/20 | 0.38 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | GGPS1 | O95749 | 1/20 | 0.36 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | AGXT | P21549 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7815680 | 0.81 | ACMSD (0.54) | ACMSDMAP4K4CDK8PRKCICYP4F2 | |
| SCHEMBL5865105 | 0.80 | TDP1 (0.62) | ACMSDMAP4K4CDK8PRKCICYP4F2 | |
| SCHEMBL7248747 | 0.77 | ACMSD (0.54) | ACMSDMAP4K4CDK8PRKCICYP4F2 | |
| SCHEMBL2571534 | 0.77 | TAAR1 (0.55) | ACMSDMAP4K4CDK8PRKCIBACE1 | |
| SCHEMBL18069884 | 0.77 | AGXT (0.57) | ACMSDMAP4K4CDK8PRKCITDP1 | |
| SCHEMBL1138646 | 0.74 | PRKCI (0.73) | ACMSDMAP4K4CDK8PRKCITDP1 | |
| SCHEMBL2652456 | 0.73 | AGXT (0.60) | ACMSDMAP4K4PRKCIAGXT | |
| SCHEMBL8954492 | 0.72 | MKNK1 (0.43) | ACMSDPRKCIBCL2MAPT | |
| SCHEMBL3238340 | 0.72 | ACMSD (0.52) | ACMSDMAP4K4CDK8PRKCICYP4F2 | |
| SCHEMBL19116929 | 0.71 | ACMSD (0.51) | ACMSDMAP4K4CDK8PRKCICYP4F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030013883-A1 | Tropane analogs binding to monoamine transporters | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2003-01-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030013883-A1 | Tropane analogs binding to monoamine transporters | SLC6A3, SLC6A2, SLC6A4 | ACMSD 3231/4885MAP4K4 4677/4885CDK8 3921/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.