Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 2/20 | 1.00 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9356448 | 0.90 | ELANE (0.81) | ELANEMAPK1ALDH1A1CYP1A2KMT2A | |
| SCHEMBL10588348 | 0.80 | ELANE (0.66) | ELANEMAPK1ALDH1A1CYP1A2KMT2A | |
| SCHEMBL11113900 | 0.79 | MAPK1 (0.78) | ELANEMAPK1ALDH1A1CYP1A2KMT2A | |
| SCHEMBL13954060 | 0.77 | ELANE (0.63) | ELANEALDH1A1CYP1A2KMT2AMEN1 | |
| SCHEMBL21007472 | 0.76 | CYP1A2 (0.73) | ELANEALDH1A1CYP1A2KMT2AMEN1 | |
| SCHEMBL14521500 | 0.76 | CYP1A2 (0.73) | ELANEALDH1A1CYP1A2KMT2AMEN1 | |
| SCHEMBL11189007 | 0.75 | ELANE (0.59) | ELANEALDH1A1KMT2AMEN1HPGD | |
| SCHEMBL11189010 | 0.75 | ELANE (0.59) | ELANEALDH1A1KMT2AMEN1HPGD | |
| SCHEMBL10589123 | 0.73 | ELANE (0.58) | ELANEMAPK1POLB | |
| SCHEMBL10589133 | 0.73 | ELANE (0.57) | ELANEMAPK1ALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 209 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260130899-A1 | METHOD OF TREATMENT FOR PREVENTION OF GLUCOCORTICOID TOXICITY AND/OR ENHANCEMENT OF MUSCLE REGENERATION VIA NEUTROPHIL ELASTASE INHIBITION | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) | 2026-05-14 | — | — | US | claimed |
| US-20250064792-A1 | MUSCLE REGENERATION | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) | 2025-02-27 | — | — | US | claimed |
| US-20240216353-A1 | METHOD OF TREATMENT FOR PREVENTION OF GLUCOCORTICOID TOXICITY AND/OR ENHANCEMENT OF MUSCLE REGENERATION VIA NEUTROPHIL ELASTASE INHIBITION | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) | 2024-07-04 | — | — | US | claimed |
| US-20230127290-A1 | MUSCLE REGENERATION | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) | 2023-04-27 | — | — | US | claimed |
| US-20210315873-A1 | METHOD OF TREATMENT FOR PREVENTION OF GLUCOCORTICOID TOXICITY AND/OR ENHANCEMENT OF MUSCLE REGENERATION VIA NEUTROPHIL ELASTASE INHIBITION | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) | 2021-10-14 | — | — | US | claimed |
| US-20210196694-A1 | MUSCLE REGENERATION | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) | 2021-07-01 | — | — | US | claimed |
| US-20190134014-A1 | MUSCLE REGENERATION | THE UNIVERSITY OF LIVERPOOL (GB) | 2019-05-09 | — | — | US | claimed |
| CN-105085428-B | Aromatic heterocyclic derivatives and its application on drug | 广东东阳光药业有限公司 | 2019-03-22 | — | — | CN | claimed |
| CN-106279138-B | Aromatic heterocyclic derivatives and its application in drug | 广东东阳光药业有限公司 | 2019-03-01 | — | — | CN | claimed |
| CN-109248319-A | Contain the pharmaceutical composition for taking charge of smooth class compound and aspirin | 郜建敏 | 2019-01-22 | — | — | CN | claimed |
| CN-107157976-A | Application of the compound of thioether acids structure in medicament for resisting platelet aggregation is prepared | 北京北朋科技有限公司 | 2017-09-15 | — | — | CN | claimed |
| CN-106279138-A | Heteroaromatic analog derivative and the application in medicine thereof | 广东东阳光药业有限公司 | 2017-01-04 | — | — | CN | claimed |
| CN-105399698-A | Aromatic heterocyclic derivatives and applications of aromatic heterocyclic derivatives in medicines | GUANGDONG HEC PHARMACEUTICAL | 2016-03-16 | — | — | CN | claimed |
| WO-2016034134-A1 | HETEROAROMATIC DERIVATIVES AND PHARMACEUTICAL APPLICATIONS THEREOF | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2016-03-10 | — | — | WO | claimed |
| CN-105085428-A | Heteroaromatic derivative and application thereof to medicament | GUANGDONG HEC PHARMACEUTICAL | 2015-11-25 | — | — | CN | claimed |
| WO-2015161830-A1 | HETEROAROMATIC DERIVATIVES AND PHARMACEUTICAL APPLICATIONS THEREOF | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2015-10-29 | — | — | WO | claimed |
| CN-101330905-A | Freeze-drying process and products obtained thereby | SCIDOSE LLC (US) | 2008-12-24 | — | — | CN | claimed |
| EP-1336602-A1 | Nitrate prodrugs able to release nitric oxide in a controlled and selective way and their use for prevention and treatment of inflammatory, ischemic and proliferative diseases | Scaramuzzino, Giovanni (IT) | 2003-08-20 | — | — | EP | claimed |
| US-4481212-A | RESPIRATORY SYSTEM DISORDERS | MEDEA RESEARCH S.R.L. (IT) | 1984-11-06 | — | — | US | claimed |
| EP-0120534-A1 | Thiolactic acid derivative with bronchosecretolitic activity | MEDEA RESEARCH S.r.l. (IT) | 1984-10-03 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260130899-A1 | METHOD OF TREATMENT FOR PREVENTION OF GLUCOCORTICOID TOXICITY AND/OR ENHANCEMENT OF MUSCLE REGENERATION VIA NEUTROPHIL ELASTASE INHIBITION | SERPINB1, ELANE, CELA1 | ELANE 2/4885MAPK1 762/4885ALDH1A1 3318/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.