Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 3/20 | 0.78 |
| ▸ | ELANE | P08246 | 1/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.62 |
| ▸ | POLB | P06746 | 1/20 | 0.61 |
| ▸ | TSHR | P16473 | 2/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | HPGD | P15428 | 2/20 | 0.56 |
| ▸ | RAB9A | P51151 | 2/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Midesteine SCHEMBL724755 | 0.79 | ELANE (1.00) | MAPK1ELANEALDH1A1POLBHSD17B10 | |
| SCHEMBL3462955 | 0.77 | ALDH1A1 (1.00) | MAPK1ALDH1A1POLBHSD17B10KMT2A | |
| SCHEMBL9356448 | 0.77 | ELANE (0.81) | MAPK1ELANEALDH1A1POLBHSD17B10 | |
| SCHEMBL825926 | 0.76 | RAB9A (0.84) | ALDH1A1TSHRHSD17B10KMT2AMEN1 | |
| SCHEMBL30597578 | 0.76 | POLB (1.00) | MAPK1ALDH1A1POLBHSD17B10KMT2A | |
| SCHEMBL30597589 | 0.74 | POLB (0.82) | MAPK1ALDH1A1POLBHSD17B10KMT2A | |
| SCHEMBL14830534 | 0.73 | KMT2A (0.72) | MAPK1ALDH1A1POLBKMT2AMEN1 | |
| SCHEMBL10511025 | 0.73 | KMT2A (0.72) | MAPK1ALDH1A1POLBKMT2AMEN1 | |
| SCHEMBL10589133 | 0.73 | ELANE (0.57) | MAPK1ELANEALDH1A1POLBRAB9A | |
| SCHEMBL12181432 | 0.73 | RAB9A (0.90) | ALDH1A1TSHRHSD17B10KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0120359-A1 | Tetrahydrothiophenone derivative active in respiratory system affections | YASON S.r.l (IT) | 1984-10-03 | — | — | EP | claimed |
| EP-0120359-A1 | Tetrahydrothiophenone derivative active in respiratory system affections | YASON S.r.l (IT) | 1984-10-03 | — | — | EP | disclosed |