Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | JAK2 | O60674 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | TOP2A | P11388 | 5/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.47 |
| ▸ | PDE4A | P27815 | 1/20 | 0.46 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.46 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.46 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7247670 | 1.00 | FDPS (0.53) | FDPSKDM4EGAAKMT2AMAPT | |
| SCHEMBL4621805 | 0.90 | KDM4E (0.62) | KDM4EGAAKMT2AMAPTALDH1A1 | |
| SCHEMBL5349276 | 0.84 | FDPS (0.72) | FDPSKDM4EGAAKMT2AMAPT | |
| SCHEMBL5349280 | 0.84 | FDPS (0.72) | FDPSKDM4EGAAKMT2AMAPT | |
| SCHEMBL2085644 | 0.83 | KDM4E (0.50) | FDPSKDM4EGAAMAPTALDH1A1 | |
| SCHEMBL2001231 | 0.80 | GAA (0.53) | FDPSKDM4EGAAKMT2AMAPT | |
| SCHEMBL2391351 | 0.80 | TTR (0.50) | FDPSMAPTALDH1A1NPC1RAB9A | |
| SCHEMBL2390189 | 0.79 | TTR (0.52) | FDPSNPC1RAB9ATTRAPP | |
| SCHEMBL4215750 | 0.79 | ALDH1A1 (0.47) | KDM4EGAAKMT2AMAPTALDH1A1 | |
| SCHEMBL4215757 | 0.79 | ALDH1A1 (0.47) | KDM4EGAAKMT2AMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6632909-B2 | Alkylenedi- acrylates and acrylamides containing phenyl groups substituted with at least two alkoxy or fluoroalkoxy groups; use in orientation layers for liquid crystals, and in optical components, in particular hybrid layer elements. | ROLIC AG (CH) | 2003-10-14 | — | — | US | disclosed |
| US-20020061996-A1 | Photocrosslinkable polymers | BUCHECKER RICHARD (CH) | 2002-05-23 | — | — | US | disclosed |