Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 2/20 | 0.40 |
| ▸ | PREP | P48147 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21958050 | 1.00 | ACE (0.40) | ACEPREPKMT2A | |
| SCHEMBL10865220 | 0.81 | ACE (0.40) | ACEKMT2A | |
| SCHEMBL19253042 | 0.78 | ACE (0.54) | ACEPREPKMT2A | |
| SCHEMBL1652402 | 0.78 | ACE (0.54) | ACEPREPKMT2A | |
| SCHEMBL9409947 | 0.78 | ACE (0.54) | ACEPREPKMT2A | |
| SCHEMBL10865901 | 0.77 | ACE (0.47) | ACEPREP | |
| SCHEMBL2681085 | 0.76 | HSD17B10 (0.47) | ACEPREP | |
| SCHEMBL21530308 | 0.76 | HSD17B10 (0.47) | ACEPREP | |
| SCHEMBL1618739 | 0.76 | HSD17B10 (0.47) | ACEPREP | |
| SCHEMBL22749708 | 0.75 | TSHR (0.33) | ACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1981862-B1 | LANTHIONINE-RELATED COMPOUNDS FOR THE TREATMENT OF INFLAMMATORY DISEASES | OKLAHOMA MED RES FOUND (US) | 2011-03-02 | — | — | EP | claimed |
| EP-1981862-A2 | LANTHIONINE-RELATED COMPOUNDS FOR THE TREATMENT OF INFLAMMATORY DISEASES | Oklahoma Medical Research Foundation (US) | 2008-10-22 | — | — | EP | claimed |
| US-20070197515-A1 | LANTHIONINE-RELATED COMPOUNDS FOR THE TREATMENT OF INFLAMMATORY DISEASES | OKLAHOMA MEDICAL RESEARCH FOUNDATION | 2007-08-23 | — | — | US | claimed |
| WO-2007082208-A2 | LANTHIONINE-RELATED COMPOUNDS FOR THE TREATMENT OF INFLAMMATORY DISEASES | OKLAHOMA MEDICAL RESEARCH FOUNDATION (US) | 2007-07-19 | — | — | WO | claimed |
| EP-3880654-A1 | 2-FORMYL-3-HYDROXYPHENYLOXYMETHYL COMPOUNDS CAPABLE OF MODULATING HEMOGLOBIN | Global Blood Therapeutics, Inc. (US) | 2021-09-22 | — | — | EP | disclosed |
| JP-5367377-B2 | — | — | 2013-12-11 | — | — | JP | disclosed |
| US-20130209366-A1 | Glutathione-Lanthionine Compounds and Methods Related Thereto | OKLAHOMA MEDICAL RESEARCH FOUNDATION (US) | 2013-08-15 | — | — | US | disclosed |
| WO-2012027455-A1 | GLUTATHIONE-LANTHIONINE COMPOUNDS AND METHODS RELATED THERETO | THE UNIVERSITY OF TOLEDO (US) | 2012-03-01 | — | — | WO | disclosed |
| EP-1981862-B1 | LANTHIONINE-RELATED COMPOUNDS FOR THE TREATMENT OF INFLAMMATORY DISEASES | OKLAHOMA MED RES FOUND (US) | 2011-03-02 | — | — | EP | disclosed |
| EP-1981862-B1 | LANTHIONINE-RELATED COMPOUNDS FOR THE TREATMENT OF INFLAMMATORY DISEASES | OKLAHOMA MED RES FOUND (US) | 2011-03-02 | — | — | EP | disclosed |
| US-7683055-B2 | Lanthionine-related compounds for the treatment of inflammatory diseases | OKLAHOMA MEDICAL RESEARCH FOUNDATION (US) | 2010-03-23 | — | — | US | disclosed |
| US-7683055-B2 | Lanthionine-related compounds for the treatment of inflammatory diseases | OKLAHOMA MEDICAL RESEARCH FOUNDATION (US) | 2010-03-23 | — | — | US | disclosed |
| EP-1981862-A2 | LANTHIONINE-RELATED COMPOUNDS FOR THE TREATMENT OF INFLAMMATORY DISEASES | Oklahoma Medical Research Foundation (US) | 2008-10-22 | — | — | EP | disclosed |
| EP-1981862-A2 | LANTHIONINE-RELATED COMPOUNDS FOR THE TREATMENT OF INFLAMMATORY DISEASES | Oklahoma Medical Research Foundation (US) | 2008-10-22 | — | — | EP | disclosed |
| WO-2007082208-A3 | LANTHIONINE-RELATED COMPOUNDS FOR THE TREATMENT OF INFLAMMATORY DISEASES | OKLAHOMA MED RES FOUND (US) | 2007-09-13 | — | — | WO | disclosed |
| US-20070197515-A1 | LANTHIONINE-RELATED COMPOUNDS FOR THE TREATMENT OF INFLAMMATORY DISEASES | OKLAHOMA MEDICAL RESEARCH FOUNDATION | 2007-08-23 | — | — | US | disclosed |
| US-20070197515-A1 | LANTHIONINE-RELATED COMPOUNDS FOR THE TREATMENT OF INFLAMMATORY DISEASES | OKLAHOMA MEDICAL RESEARCH FOUNDATION | 2007-08-23 | — | — | US | disclosed |
| WO-2007082208-A2 | LANTHIONINE-RELATED COMPOUNDS FOR THE TREATMENT OF INFLAMMATORY DISEASES | OKLAHOMA MEDICAL RESEARCH FOUNDATION (US) | 2007-07-19 | — | — | WO | disclosed |
| WO-2007082208-A2 | LANTHIONINE-RELATED COMPOUNDS FOR THE TREATMENT OF INFLAMMATORY DISEASES | OKLAHOMA MEDICAL RESEARCH FOUNDATION (US) | 2007-07-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130209366-A1 | Glutathione-Lanthionine Compounds and Methods Related Thereto | GPX1, GCLC, GSS | ACE 730/4885PREP 456/4885KMT2A 2883/4885 |
| US-20070197515-A1 | LANTHIONINE-RELATED COMPOUNDS FOR THE TREATMENT OF INFLAMMATORY DISEASES | SLC7A11, AADAT, TSPO | ACE 2702/4885PREP 2133/4885KMT2A 1195/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.