SCHEMBL14848625

SCHEMBL14848625

Cc1ccc2c(c1)c1cc(N(c3ccccc3)c3ccc4ccc5c(N(c6ccccc6)c6ccc7c(c6)c6cc(C)ccc6n7-c6ccccc6)ccc6ccc3c4c65)ccc1n2-c1ccccc1

nearest known ligand 0.33

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ GAA P10253 1/20 0.33
▸ GFER P55789 1/20 0.33
▸ KDM4E B2RXH2 3/20 0.33
▸ ATM Q13315 1/20 0.33
▸ L3MBTL1 Q9Y468 1/20 0.33
▸ HTT P42858 3/20 0.32
▸ SMN1; SMN2 Q16637 2/20 0.32
▸ HPGD P15428 2/20 0.32
▸ LMNA P02545 1/20 0.32
▸ KMT2A Q03164 3/20 0.32
▸ MEN1 O00255 2/20 0.32
▸ NR1I2 O75469 1/20 0.32
▸ AHR P35869 1/20 0.32
▸ PDE10A Q9Y233 2/20 0.32
▸ NPC1 O15118 1/20 0.32
▸ RAB9A P51151 1/20 0.32
▸ NLRP3 Q96P20 1/20 0.32
▸ MAPT P10636 3/20 0.31
▸ CYP19A1 P11511 1/20 0.31
▸ ALDH1A1 P00352 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14848622 0.92 NLRP3 (0.32) GAAGFERKDM4EATML3MBTL1
SCHEMBL7254005 0.92 HPGD (0.33) GAAGFERKDM4EATML3MBTL1
SCHEMBL14848555 0.90 KDM4E (0.39) GAAGFERKDM4EATML3MBTL1
SCHEMBL7248759 0.89 L3MBTL1 (0.35) KDM4EATML3MBTL1HPGDAHR
SCHEMBL14848517 0.89 KDM4E (0.45) KDM4EATML3MBTL1KMT2AMEN1
SCHEMBL16001347 0.88 PDE10A (0.32) GAAGFERHTTSMN1; SMN2HPGD
SCHEMBL18416098 0.87 KDM4E (0.33) GAAKDM4EATML3MBTL1LMNA
SCHEMBL14848549 0.86 KDM4E (0.34) KDM4EATML3MBTL1HTTHPGD
SCHEMBL21475585 0.85 KDM4E (0.35) KDM4EATML3MBTL1
SCHEMBL18416099 0.85 KDM4E (0.33) GAAKDM4EATML3MBTL1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230403926-A1 ORGANIC LIGHT-EMITTING DEVICE WITH IMPROVED LIFESPAN CHARACTERISTICS UNIVERSITY-INDUSTRY COOPERATION GROUP OF KYUNG HEE UNIVERSITY (KR) 2023-12-14 — — US disclosed
US-20230403926-A1 ORGANIC LIGHT-EMITTING DEVICE WITH IMPROVED LIFESPAN CHARACTERISTICS UNIVERSITY-INDUSTRY COOPERATION GROUP OF KYUNG HEE UNIVERSITY (KR) 2023-12-14 — — US disclosed
US-11158812-B2 Light-emitting element, light-emitting device, electronic device, lighting device, and pyrene-based compound SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2021-10-26 — — US disclosed
US-20190273207-A1 Light-Emitting Element, Light-Emitting Device, Electronic Device, Lighting Device, and Pyrene-Based Compound SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2019-09-05 — — US disclosed
US-10230052-B2 Light-emitting element, light-emitting device, electronic device, lighting device, and pyrene-based compound SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2019-03-12 — — US disclosed
US-20180190905-A1 Light-Emitting Element, Light-Emitting Device, Electronic Device, Lighting Device, and Pyrene-Based Compound SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2018-07-05 — — US disclosed
US-20180190905-A1 Light-Emitting Element, Light-Emitting Device, Electronic Device, Lighting Device, and Pyrene-Based Compound SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2018-07-05 — — US disclosed
US-9911923-B2 Light-emitting element, light-emitting device, electronic device, lighting device, and pyrene-based compound SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2018-03-06 — — US disclosed
US-9911923-B2 Light-emitting element, light-emitting device, electronic device, lighting device, and pyrene-based compound SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2018-03-06 — — US disclosed
US-20160254451-A1 Light-Emitting Element, Light-Emitting Device, Electronic Device, Lighting Device, and Pyrene-Based Compound SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2016-09-01 — — US disclosed
US-20160254451-A1 Light-Emitting Element, Light-Emitting Device, Electronic Device, Lighting Device, and Pyrene-Based Compound SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2016-09-01 — — US disclosed
US-9343681-B2 Light-emitting element, light-emitting device, electronic device, lighting device, and pyrene-based compound SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2016-05-17 — — US disclosed
US-9343681-B2 Light-emitting element, light-emitting device, electronic device, lighting device, and pyrene-based compound SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2016-05-17 — — US disclosed
US-20130087773-A1 Light-Emitting Element, Light-Emitting Device, Electronic Device, Lighting Device, and Pyrene-Based Compound SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2013-04-11 — — US disclosed
US-20130087773-A1 Light-Emitting Element, Light-Emitting Device, Electronic Device, Lighting Device, and Pyrene-Based Compound SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2013-04-11 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130087773-A1 Light-Emitting Element, Light-Emitting Device, Electronic Device, Lighting Device, and Pyrene-Based Compound PPOX, PNPO, ESR1 GAA 3120/4885GFER 1201/4885KDM4E 1990/4885
US-20180190905-A1 Light-Emitting Element, Light-Emitting Device, Electronic Device, Lighting Device, and Pyrene-Based Compound PPOX, PNPO, ESR1 GAA 3120/4885GFER 1201/4885KDM4E 1990/4885
US-20190273207-A1 Light-Emitting Element, Light-Emitting Device, Electronic Device, Lighting Device, and Pyrene-Based Compound PPOX, PNPO, ESR1 GAA 3120/4885GFER 1201/4885KDM4E 1990/4885
US-10230052-B2 Light-emitting element, light-emitting device, electronic device, lighting device, and pyrene-based compound PPOX, PNPO, ESR1 GAA 3120/4885GFER 1201/4885KDM4E 1990/4885
US-20230403926-A1 ORGANIC LIGHT-EMITTING DEVICE WITH IMPROVED LIFESPAN CHARACTERISTICS ELP1, ELOVL1, L3MBTL1 GAA 1782/4885GFER 1235/4885KDM4E 3119/4885
US-11158812-B2 Light-emitting element, light-emitting device, electronic device, lighting device, and pyrene-based compound PPOX, PNPO, ESR1 GAA 3120/4885GFER 1201/4885KDM4E 1990/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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