Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 5/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 5/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 4/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 4/20 | 0.33 |
| ▸ | PDE4A | P27815 | 3/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.33 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.33 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.32 |
| ▸ | MRGPRX2 | Q96LB1 | 1/20 | 0.31 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethylene SCHEMBL7253122 | 0.82 | PDE4D (0.44) | LMNAKDM4EALDH1A1HSD17B10MAPT | |
| Ethylene SCHEMBL7250517 | 0.82 | LMNA (0.44) | LMNAKDM4EALDH1A1HSD17B10MAPT | |
| Ethylene SCHEMBL7250284 | 0.81 | PDE4D (0.45) | LMNAKDM4EALDH1A1HSD17B10MAPT | |
| SCHEMBL6602656 | 0.78 | ALDH1A1 (0.48) | LMNAKDM4EALDH1A1HSD17B10MAPT | |
| SCHEMBL6607682 | 0.78 | PDE4D (0.46) | LMNAKDM4EALDH1A1HSD17B10MAPT | |
| SCHEMBL7249854 | 0.76 | KDM4E (0.46) | LMNAKDM4EALDH1A1HSD17B10MAPT | |
| SCHEMBL7256850 | 0.76 | LMNA (0.46) | LMNAKDM4EALDH1A1HSD17B10MAPT | |
| SCHEMBL7249855 | 0.76 | KDM4E (0.46) | LMNAKDM4EALDH1A1HSD17B10MAPT | |
| SCHEMBL7256680 | 0.75 | LMNA (0.45) | LMNAKDM4EALDH1A1HSD17B10MAPT | |
| SCHEMBL7256677 | 0.75 | LMNA (0.45) | LMNAKDM4EALDH1A1HSD17B10MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030100772-A1 | Oxygen-containing heterocyclic compounds | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2003-05-29 | — | — | US | disclosed |
| EP-1264829-A1 | OXYGEN-CONTAINING HETEROCYCLIC COMPOUNDS | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2002-12-11 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030100772-A1 | Oxygen-containing heterocyclic compounds | CBR1, CYP11B2, CBR3 | LMNA 4580/4885KDM4E 1212/4885ALDH1A1 263/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.