Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 6/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 6/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 6/20 | 0.39 |
| ▸ | HTR1A | P08908 | 4/20 | 0.39 |
| ▸ | IKBKB | O14920 | 1/20 | 0.39 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.38 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | MAPK11 | Q15759 | 2/20 | 0.36 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.36 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.36 |
| ▸ | RAF1 | P04049 | 1/20 | 0.36 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.36 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1119443 | 0.85 | LMNA (0.42) | IKBKBLMNAMAPTHTTSMN1; SMN2 | |
| SCHEMBL652509 | 0.81 | NPC1 (0.42) | IKBKBLMNAMAPTHTTSMN1; SMN2 | |
| SCHEMBL5213208 | 0.81 | MAOB (0.51) | SLC6A2SLC6A4SLC6A3HTR1A | |
| SCHEMBL6002534 | 0.80 | HTR3A (0.44) | SLC6A2SLC6A4SLC6A3IKBKB | |
| SCHEMBL6002937 | 0.79 | SLC18A3 (0.48) | LMNA | |
| SCHEMBL16861712 | 0.76 | MAPT (0.37) | LMNAMAPTHTTSMN1; SMN2 | |
| SCHEMBL8481040 | 0.76 | AKT1 (0.39) | SLC6A2SLC6A4SLC6A3IKBKBMKNK1 | |
| SCHEMBL27697688 | 0.75 | EPHX1 (0.47) | SLC6A4 | |
| SCHEMBL20015401 | 0.74 | MAOB (0.46) | — | |
| Trifluoroacetic Acid SCHEMBL19994588 | 0.73 | HSD11B1 (0.42) | SLC6A2SLC6A4SLC6A3LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6521614-B1 | Anticoagulant agents for treatment and prevention of thromboembolic disorders | BRISTOL-MYERS SQUIBB PHARMA COMPANY | 2003-02-18 | — | — | US | disclosed |